Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162845 | 1.00 | ALDH1A1 (0.64) | ALDH1A1LMNAGLAGAARAB9A | |
| SCHEMBL7412076 | 0.91 | ALDH1A1 (0.54) | ALDH1A1LMNAGLAGAARAB9A | |
| SCHEMBL15446286 | 0.86 | PTPN1 (0.57) | ALDH1A1LMNAGLAGAARAB9A | |
| SCHEMBL1793176 | 0.85 | GAA (0.76) | ALDH1A1LMNAGLAGAARAB9A | |
| SCHEMBL2461492 | 0.85 | GAA (0.76) | ALDH1A1LMNAGLAGAARAB9A | |
| SCHEMBL9208207 | 0.85 | ATM (0.57) | ALDH1A1LMNAGLAGAARAB9A | |
| SCHEMBL31206887 | 0.85 | GAA (0.76) | ALDH1A1LMNAGLAGAARAB9A | |
| SCHEMBL5162493 | 0.84 | ACE (0.56) | TACR1PIN1CTSLCA2ACE | |
| SCHEMBL5162484 | 0.84 | ACE (0.56) | TACR1PIN1CTSLCA2ACE | |
| SCHEMBL3739594 | 0.81 | ATM (0.60) | ALDH1A1LMNAGLAGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763361-A2 | STEROID SPARING AGENTS AND THEIR USE | Elan Pharmaceuticals, Inc. (US) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005097162-A2 | STEROID SPARING AGENTS AND THEIR USE | ELAN PHARMACEUTICALS, INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| EP-1144435-A2 | PYROGLUTAMIC ACID DERIVATIVES AND RELATED COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | Elan Pharmaceuticals, Inc. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000043413-A2 | PYROGLUTAMIC ACID DERIVATIVES AND RELATED COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARMACEUTICALS, INC. (US) | 2000-07-27 | — | — | WO | disclosed |