Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.87 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.87 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139301 | 0.93 | DPP4 (1.00) | DPP4DPP8CYP11B1CYP11B2TP53 | |
| SCHEMBL3143840 | 0.86 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL3135758 | 0.75 | DPP4 (0.68) | DPP4DPP8CYP11B1CYP11B2TP53 | |
| SCHEMBL3144355 | 0.75 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL3153018 | 0.75 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL3144437 | 0.65 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL3154186 | 0.65 | DPP4 (1.00) | DPP4DPP8 | |
| SCHEMBL10175447 | 0.64 | CYP11B2 (0.60) | DPP4DPP8CYP11B1CYP11B2 | |
| SCHEMBL30663918 | 0.62 | CYP11B2 (0.54) | DPP4DPP8CYP11B1CYP11B2 | |
| SCHEMBL26603247 | 0.62 | CYP11B2 (0.54) | DPP4DPP8CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753730-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2007-02-21 | — | — | EP | claimed |
| WO-2005118555-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-12-15 | — | — | WO | claimed |