Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 7/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5163364 | 1.00 | PLA2G2C (0.43) | PLA2G2CPLA2G2AKMT2APOLBMGAM | |
| SCHEMBL4205996 | 1.00 | PLA2G2C (0.43) | PLA2G2CPLA2G2AKMT2APOLBMGAM | |
| SCHEMBL5327674 | 0.91 | MGAM (0.37) | PLA2G2CPLA2G2AKMT2APOLBMGAM | |
| SCHEMBL4195616 | 0.91 | MGAM (0.37) | PLA2G2CPLA2G2AKMT2APOLBMGAM | |
| SCHEMBL4936189 | 0.91 | MGAM (0.37) | PLA2G2CPLA2G2AKMT2APOLBMGAM | |
| SCHEMBL5166981 | 0.91 | MGAM (0.37) | PLA2G2CPLA2G2AKMT2APOLBMGAM | |
| SCHEMBL592891 | 0.86 | PLA2G2C (0.53) | PLA2G2CPLA2G2AKMT2APOLBMGAM | |
| SCHEMBL4204036 | 0.85 | MGAM (0.39) | KMT2APOLBMGAMGAASI | |
| SCHEMBL5180093 | 0.85 | MGAM (0.39) | KMT2APOLBMGAMGAASI | |
| SCHEMBL4205637 | 0.82 | PLA2G2C (0.44) | PLA2G2CPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768952-A2 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | Warner-Lambert Company LLC (US) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006008612-A2 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | WARNER-LAMBERT COMPANY LLC (US) | 2006-01-26 | — | — | WO | disclosed |