Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166981 | 1.00 | MGAM (0.37) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL4195616 | 1.00 | MGAM (0.37) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL4936189 | 1.00 | MGAM (0.37) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL5163364 | 0.91 | PLA2G2C (0.43) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL5163368 | 0.91 | PLA2G2C (0.43) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL4205996 | 0.91 | PLA2G2C (0.43) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL5180093 | 0.88 | MGAM (0.39) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL4204036 | 0.88 | MGAM (0.39) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL1405748 | 0.85 | MGAM (0.43) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL4156137 | 0.84 | CNR2 (0.42) | MGAMGAASIMGAM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863780-A1 | PREPARATION OF OPTICALLY PURE BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | Pharmacia & Upjohn Company LLC (US) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006100568-A1 | PREPARATION OF OPTICALLY PURE BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |