Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166981 | 1.00 | MGAM (0.37) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL5327674 | 1.00 | MGAM (0.37) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL4195616 | 1.00 | MGAM (0.37) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL5163364 | 0.91 | PLA2G2C (0.43) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL5163368 | 0.91 | PLA2G2C (0.43) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL4205996 | 0.91 | PLA2G2C (0.43) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL5180093 | 0.88 | MGAM (0.39) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL4204036 | 0.88 | MGAM (0.39) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL1405748 | 0.85 | MGAM (0.43) | MGAMGAASIMGAM2PLA2G2C | |
| SCHEMBL4156137 | 0.84 | CNR2 (0.42) | MGAMGAASIMGAM2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194841-A1 | Preparation of Optically Pure Beta-Amino Acids Having Affinity for the Alpha-Delta Protein | PFIZER INC. | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194841-A1 | Preparation of Optically Pure Beta-Amino Acids Having Affinity for the Alpha-Delta Protein | OPRD1, CHRND, CHRNE | MGAM 4420/4885GAA 2065/4885SI 2275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.