SCHEMBL5163863

SCHEMBL5163863

CCCCCCCCCCCCCCCCCCC(F)(C(=O)O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.46
LPAR1 Q92633 1/20 0.42
LPAR3 Q9UBY5 1/20 0.42
THRB P10828 1/20 0.41
FAAH O00519 8/20 0.40
CES1 P23141 5/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
KMT2A Q03164 1/20 0.40
HSD17B10 Q99714 1/20 0.40
EPHX1 P07099 1/20 0.37
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
SLC22A8 Q8TCC7 1/20 0.36
GPR84 Q9NQS5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11782533 0.93 THRB (0.43) CES2LPAR1LPAR3THRBFAAH
SCHEMBL6250219 0.85 CES2 (0.52) CES2LPAR1LPAR3FAAHCES1
SCHEMBL9511027 0.85 CES2 (0.52) CES2LPAR1LPAR3FAAHCES1
SCHEMBL6251798 0.85 CES2 (0.52) CES2LPAR1LPAR3FAAHCES1
SCHEMBL6251804 0.85 CES2 (0.52) CES2LPAR1LPAR3FAAHCES1
SCHEMBL9508938 0.85 CES2 (0.52) CES2LPAR1LPAR3FAAHCES1
SCHEMBL6250222 0.85 CES2 (0.52) CES2LPAR1LPAR3FAAHCES1
SCHEMBL9508334 0.85 CES2 (0.52) CES2LPAR1LPAR3FAAHCES1
SCHEMBL9512023 0.83 CES2 (0.48) CES2LPAR1LPAR3FAAHCES1
SCHEMBL29098829 0.82 CES2 (0.46) CES2LPAR1LPAR3THRBFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1768112-A1 Perpendicular magnetic recording medium and method for manufacturing the same FUJIFILM Corporation (JP) 2007-03-28 EP disclosed
US-20070065682-A1 Perpendicular magnetic recording medium having nanoparticle soft magnetic layer and method for manufacturing the same FUJI PHOTO FILM CO., LTD. 2007-03-22 US disclosed