SCHEMBL5163877

SCHEMBL5163877

CCn1c2ccccc2c2cc(C(O)O)ccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.59
MAPT P10636 6/20 0.59
KMT2A Q03164 4/20 0.59
MEN1 O00255 3/20 0.59
ALDH1A1 P00352 3/20 0.59
HTT P42858 2/20 0.59
MAPK1 P28482 2/20 0.59
HPGD P15428 1/20 0.59
HBB P68871 1/20 0.59
HSD17B10 Q99714 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
LMNA P02545 5/20 0.55
POLB P06746 2/20 0.55
PKM P14618 1/20 0.55
NPSR1 Q6W5P4 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.49
SRC P12931 2/20 0.49
NPY5R Q15761 2/20 0.49
NPY2R P49146 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL253310 0.87 MAPT (0.63) KDM4EMAPTKMT2AMEN1ALDH1A1
SCHEMBL8232713 0.85 MAPT (0.61) KDM4EMAPTKMT2AMEN1ALDH1A1
SCHEMBL13171438 0.83 MAPT (0.58) KDM4EMAPTKMT2AMEN1ALDH1A1
SCHEMBL3156176 0.83 MAPT (0.58) KDM4EMAPTKMT2AMEN1ALDH1A1
SCHEMBL16639876 0.83 MAPT (0.58) KDM4EMAPTKMT2AMEN1ALDH1A1
SCHEMBL23918440 0.83 MAPT (0.58) KDM4EMAPTKMT2AMEN1ALDH1A1
SCHEMBL6320904 0.83 MAPT (0.62) KDM4EMAPTKMT2AMEN1ALDH1A1
SCHEMBL6321844 0.81 MAPT (0.52) KDM4EMAPTKMT2AMEN1ALDH1A1
SCHEMBL23175746 0.81 KDM4E (0.49) KDM4EMAPTKMT2AMEN1ALDH1A1
SCHEMBL23175748 0.81 KDM4E (0.49) KDM4EMAPTKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1530094-B1 Organophotoreceptor with charge transport material having three arylamino groups SAMSUNG ELECTRONICS CO LTD (KR) 2007-02-28 EP disclosed
US-7132209-B2 Organophotoreceptor with charge transport material having three arylamino groups SAMSUNG ELECTRONICS CO., LTD (KR) 2006-11-07 US disclosed
EP-1530094-A2 Organophotoreceptor with charge transport material having three arylamino groups Samsung Electronics Co., Ltd. (KR) 2005-05-11 EP disclosed
US-20050095518-A1 photoconductive element with bis(hydrazone) carbazole compounds of given formula as charge transport material; electrophotographic apparatus and imaging method; good electrostatic properties S-PRINTING SOLUTION CO., LTD. (KR) 2005-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050095518-A1 photoconductive element with bis(hydrazone) carbazole compounds of given formula as charge transport material; electrophotographic apparatus and imaging method; good electrostatic properties CHRM5, NR2E3, CHRM3 KDM4E 2949/4885MAPT 3367/4885KMT2A 2835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.