Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HBB | P68871 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253310 | 0.95 | MAPT (0.63) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL14526612 | 0.88 | MAPT (0.49) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL4635172 | 0.87 | MAPT (0.51) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL2108365 | 0.87 | MAPT (0.55) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL8232713 | 0.84 | MAPT (0.61) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL10666862 | 0.83 | TP53 (0.60) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL5163877 | 0.83 | KDM4E (0.59) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL14532708 | 0.82 | MAPT (0.41) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL254024 | 0.82 | MAPT (0.52) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL30898583 | 0.82 | MAPT (0.52) | MAPTKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437122-B1 | Composition for dyeing keratinic fibers comprising diheteroarylmethane direct dye and dyeing process using this composition | OREAL (FR) | 2010-03-03 | — | — | EP | disclosed |
| US-7217297-B2 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-15 | — | — | US | disclosed |
| US-7217297-B2 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-15 | — | — | US | disclosed |
| US-20040187229-A1 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2004-09-30 | — | — | US | disclosed |
| EP-1437122-A1 | Composition for dyeing keratinic fibers comprising a diheteroarylmethane direct dye or its lecuco precursor and dyeing process using this composition | L'OREAL (FR) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040187229-A1 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | KRT18, KMO, DLD | MAPT 433/4885KDM4E 819/4885ALDH1A1 1560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.