Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | HBB | P68871 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RORA | P35398 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8232713 | 0.87 | MAPT (0.61) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL253310 | 0.85 | MAPT (0.63) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL23918440 | 0.84 | MAPT (0.58) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL13171438 | 0.84 | MAPT (0.58) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL16639876 | 0.84 | MAPT (0.58) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL5163877 | 0.83 | KDM4E (0.59) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3156176 | 0.81 | MAPT (0.58) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL6482796 | 0.78 | MAPT (0.51) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL13084772 | 0.78 | RORC (0.54) | MAPTKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL2108365 | 0.78 | MAPT (0.55) | MAPTKDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032129-A1 | Detection of antigen by immunohistochemical staining | KAGOSHIMA UNIVERSITY (JP) | 2005-02-10 | — | — | US | disclosed |