Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 11/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 10/20 | 0.57 |
| ▸ | FPR2 | P25090 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164476 | 1.00 | ALDH1A1 (0.57) | ALDH1A1GAAITGA4ITGB1FPR2 | |
| SCHEMBL2830729 | 0.90 | ATM (0.53) | ALDH1A1GAAITGA4ITGB7 | |
| SCHEMBL2830730 | 0.90 | ATM (0.53) | ALDH1A1GAAITGA4ITGB7 | |
| SCHEMBL7424677 | 0.85 | ALDH1A1 (0.57) | ALDH1A1GAAITGA4ITGB1FPR2 | |
| SCHEMBL7386258 | 0.85 | ALDH1A1 (0.57) | ALDH1A1GAAITGA4ITGB1FPR2 | |
| SCHEMBL7382357 | 0.80 | CYP3A4 (0.55) | ALDH1A1GAAITGA4ITGB1FPR2 | |
| SCHEMBL7382884 | 0.79 | POLB (0.52) | ALDH1A1GAAITGA4ITGB1FPR2 | |
| SCHEMBL7390734 | 0.78 | ALDH1A1 (0.67) | ALDH1A1GAAITGA4FPR2ALOX15 | |
| SCHEMBL5215651 | 0.78 | ALDH1A1 (0.67) | ALDH1A1GAAITGA4FPR2ALOX15 | |
| SCHEMBL6368357 | 0.77 | ALDH1A1 (0.62) | ALDH1A1GAAFPR2ALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763361-A2 | STEROID SPARING AGENTS AND THEIR USE | Elan Pharmaceuticals, Inc. (US) | 2007-03-21 | — | — | EP | disclosed |
| WO-2005097162-A2 | STEROID SPARING AGENTS AND THEIR USE | ELAN PHARMACEUTICALS, INC. (US) | 2005-10-20 | — | — | WO | disclosed |