Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2830730 | 1.00 | ATM (0.53) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL5164476 | 0.90 | ALDH1A1 (0.57) | ALDH1A1ITGA4ITGB7GAA | |
| SCHEMBL5164472 | 0.90 | ALDH1A1 (0.57) | ALDH1A1ITGA4ITGB7GAA | |
| SCHEMBL27880853 | 0.80 | ATM (0.60) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL7689142 | 0.79 | TAAR1 (0.48) | ATMOPRK1 | |
| SCHEMBL5608554 | 0.79 | IDO1 (0.56) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL5608557 | 0.79 | IDO1 (0.56) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL28613885 | 0.78 | HPGD (0.58) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL5608495 | 0.77 | FPR2 (0.62) | ATMALDH1A1THRBCYP2C9CYP2C19 | |
| SCHEMBL5608490 | 0.77 | FPR2 (0.62) | ATMALDH1A1THRBCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2161254-A1 | Intermediate for preparing a biaryl compound | Sumitomo Chemical Company, Limited (JP) | 2010-03-10 | — | — | EP | disclosed |