SCHEMBL5164541

SCHEMBL5164541

CCC[CH]O[Si](CC)(CC)CC

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4029434 0.84 TSHR (0.36) TSHRALDH1A1
SCHEMBL9201192 0.81
SCHEMBL2343550 0.77
SCHEMBL5164728 0.74
SCHEMBL21044841 0.70 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL21044839 0.70 ALDH1A1 (0.30) TSHRALDH1A1
SCHEMBL11755979 0.69
SCHEMBL2345667 0.67
SCHEMBL703176 0.67 TSHR (0.32) TSHR
SCHEMBL21044862 0.65 TSHR (0.33) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0680478-A1 N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS G.D. SEARLE & CO. (US) 1995-11-08 EP claimed
EP-0670838-A1 SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS G.D. SEARLE & CO. (US) 1995-09-13 EP claimed
US-5359073-A Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists G. D. SEARLE & CO. (US) 1994-10-25 US claimed
WO-1994017063-A1 N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS G.D. SEARLE & CO. (US) 1994-08-04 WO claimed
WO-1994012500-A1 SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS G.D. SEARLE & CO. (US) 1994-06-09 WO claimed
US-5262426-A Treatment of cardiovascular disorders, antiinflammatory agents G. D. SEARLE & CO. (US) 1993-11-16 US claimed
EP-2518087-A1 MODIFIED MICROFIBRILLATED CELLULOSE AND RESIN COMPOSITE MATERIAL COMPRISING THE SAME DIC Corporation (JP) 2012-10-31 EP disclosed
EP-1306399-B1 Photocurable primer composition and coating method by use of the same KANSAI PAINT CO LTD (JP) 2007-03-28 EP disclosed
US-6844029-B2 Photocurable primer composition and coating method by use of the same KANSAI PAINT CO., LTD. 2005-01-18 US disclosed
US-20030109595-A1 Photocurable primer composition and coating method by use of the same KANSAI PAINT CO., LTD. (JP) 2003-06-12 US disclosed
EP-1306399-A1 Photocurable primer composition and coating method by use of the same KANSAI PAINT CO., LTD. (JP) 2003-05-02 EP disclosed
EP-0680478-A1 N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS G.D. SEARLE & CO. (US) 1995-11-08 EP disclosed
EP-0670838-A1 SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS G.D. SEARLE & CO. (US) 1995-09-13 EP disclosed
US-5359073-A Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists G. D. SEARLE & CO. (US) 1994-10-25 US disclosed
WO-1994017063-A1 N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS G.D. SEARLE & CO. (US) 1994-08-04 WO disclosed
WO-1994012500-A1 SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS G.D. SEARLE & CO. (US) 1994-06-09 WO disclosed
US-5262426-A Treatment of cardiovascular disorders, antiinflammatory agents G. D. SEARLE & CO. (US) 1993-11-16 US disclosed
US-4374755-A AS POLYMERIZATION CATALYSTS CONOCO INC. (US) 1983-02-22 US disclosed
EP-0068471-A1 Methods or preparing magnesium disiloxide compounds Conoco Phillips Company (US) 1983-01-05 EP disclosed