⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5679512 | 0.79 | TSHR (0.42) | — | |
| SCHEMBL2345981 | 0.75 | — | — | |
| SCHEMBL5164541 | 0.74 | TSHR (0.30) | — | |
| SCHEMBL703176 | 0.74 | TSHR (0.32) | — | |
| SCHEMBL6056027 | 0.72 | — | — | |
| SCHEMBL9201192 | 0.72 | — | — | |
| SCHEMBL11755979 | 0.70 | — | — | |
| SCHEMBL10600389 | 0.70 | — | — | |
| SCHEMBL6959541 | 0.67 | — | — | |
| SCHEMBL37658 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680478-A1 | N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-11-08 | — | — | EP | claimed |
| EP-0670838-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO 4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1995-09-13 | — | — | EP | claimed |
| US-5359073-A | Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists | G. D. SEARLE & CO. (US) | 1994-10-25 | — | — | US | claimed |
| WO-1994017063-A1 | N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE 4H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-08-04 | — | — | WO | claimed |
| WO-1994012500-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-06-09 | — | — | WO | claimed |
| US-5304623-A | Comprising a polyetherurethane, a vinyl polymer having pendant siloxy groups and a partially blocked solid polyisocyanate; adhesives; auto windshields; storage stability | SUNSTAR GIKEN KABUSHIKI KAISHA (JP) | 1994-04-19 | — | — | US | claimed |
| US-5262426-A | Treatment of cardiovascular disorders, antiinflammatory agents | G. D. SEARLE & CO. (US) | 1993-11-16 | — | — | US | claimed |
| EP-2518087-A1 | MODIFIED MICROFIBRILLATED CELLULOSE AND RESIN COMPOSITE MATERIAL COMPRISING THE SAME | DIC Corporation (JP) | 2012-10-31 | — | — | EP | disclosed |
| EP-1306399-B1 | Photocurable primer composition and coating method by use of the same | KANSAI PAINT CO LTD (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-6844029-B2 | Photocurable primer composition and coating method by use of the same | KANSAI PAINT CO., LTD. | 2005-01-18 | — | — | US | disclosed |
| US-20030109595-A1 | Photocurable primer composition and coating method by use of the same | KANSAI PAINT CO., LTD. (JP) | 2003-06-12 | — | — | US | disclosed |
| EP-1306399-A1 | Photocurable primer composition and coating method by use of the same | KANSAI PAINT CO., LTD. (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-5945483-A | High solids content resin composition, high solids content type paint, and painting process using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-31 | — | — | US | disclosed |
| US-5359073-A | Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists | G. D. SEARLE & CO. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994012500-A1 | SUBSTITUTED-PHENYL(N,N'-CYCLOALKYL/ALKYL CARBOXAMIDE)-1H/3H-IMIDAZO[4,5-b]PYRIDINE COMPOUNDS AS PAF ANTAGONISTS | G.D. SEARLE & CO. (US) | 1994-06-09 | — | — | WO | disclosed |
| US-5304623-A | Comprising a polyetherurethane, a vinyl polymer having pendant siloxy groups and a partially blocked solid polyisocyanate; adhesives; auto windshields; storage stability | SUNSTAR GIKEN KABUSHIKI KAISHA (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5262426-A | Treatment of cardiovascular disorders, antiinflammatory agents | G. D. SEARLE & CO. (US) | 1993-11-16 | — | — | US | disclosed |
| EP-0231932-B1 | COATING RESIN COMPOSITION | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-5061749-A | Polyurethane, vinyl polymer containing siloxy groups, filler and plasticizers | SUNSTAR GIKEN KABUSHIKI KAISHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0231932-A2 | Coating resin composition | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1987-08-12 | — | — | EP | disclosed |