⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5167406 | 0.92 | — | — | |
| SCHEMBL4684214 | 0.90 | ALDH1A1 (0.67) | — | |
| SCHEMBL2783340 | 0.82 | — | — | |
| SCHEMBL1392323 | 0.80 | ALDH1A1 (0.54) | — | |
| SCHEMBL228309 | 0.78 | — | — | |
| SCHEMBL1682671 | 0.78 | — | — | |
| SCHEMBL82451 | 0.78 | — | — | |
| SCHEMBL907647 | 0.76 | — | — | |
| SCHEMBL31549369 | 0.76 | ALDH1A1 (0.62) | — | |
| SCHEMBL2547447 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239868-A | Carbamate substituted styryl sulfone compound and preparation method and application thereof | 华夏生生药业(北京)有限公司 | 2024-06-25 | — | — | CN | claimed |
| EP-4001263-B1 | CARBAMATE-SUBSTITUTED STYRYL SULFONE COMPOUND, PREPARATION METHOD, AND APPLICATION THEREOF | HUAXIASHENGSHENG PHARMACEUTICAL BEIJING CO LTD (CN) | 2024-03-27 | — | — | EP | claimed |
| EP-4001263-A1 | CARBAMATE-SUBSTITUTED STYRYL SULFONE COMPOUND, PREPARATION METHOD, AND APPLICATION THEREOF | Huaxiashengsheng Pharmaceutical Beijing Co., Ltd. (CN) | 2022-05-25 | — | — | EP | claimed |
| CN-114072380-A | Carbamate substituted styryl sulfone compound and preparation method and application thereof | 华夏生生药业(北京)有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-118239868-A | Carbamate substituted styryl sulfone compound and preparation method and application thereof | 华夏生生药业(北京)有限公司 | 2024-06-25 | — | — | CN | disclosed |
| EP-4001263-B1 | CARBAMATE-SUBSTITUTED STYRYL SULFONE COMPOUND, PREPARATION METHOD, AND APPLICATION THEREOF | HUAXIASHENGSHENG PHARMACEUTICAL BEIJING CO LTD (CN) | 2024-03-27 | — | — | EP | disclosed |
| CN-114072380-B | Carbamate substituted styryl sulfone compound and preparation method and application thereof | 华夏生生药业(北京)有限公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-4001263-A1 | CARBAMATE-SUBSTITUTED STYRYL SULFONE COMPOUND, PREPARATION METHOD, AND APPLICATION THEREOF | Huaxiashengsheng Pharmaceutical Beijing Co., Ltd. (CN) | 2022-05-25 | — | — | EP | disclosed |
| CN-114072380-A | Carbamate substituted styryl sulfone compound and preparation method and application thereof | 华夏生生药业(北京)有限公司 | 2022-02-18 | — | — | CN | disclosed |
| US-9263767-B2 | Electrolyte solution for electrochemical devices | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20140162143-A1 | ELECTROLYTE SOLUTION FOR ELECTROCHEMICAL DEVICES | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-06-12 | — | — | US | disclosed |
| EP-2738862-A1 | ELECTROLYTE SOLUTION FOR ELECTROCHEMICAL DEVICES | Wako Pure Chemical Industries, Ltd. (JP) | 2014-06-04 | — | — | EP | disclosed |
| EP-0665015-A2 | Combination treatment for osteoporosis | ELI LILLY AND COMPANY (US) | 1995-08-02 | — | — | EP | disclosed |
| EP-0657162-A1 | Methods for lowering serum cholesterol | ELI LILLY AND COMPANY (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0651998-A1 | Methods for inhibiting bone loss | ELI LILLY AND COMPANY (US) | 1995-05-10 | — | — | EP | disclosed |
| EP-0650724-A1 | Methods for inhibiting uterine fibrosis | ELI LILLY AND COMPANY (US) | 1995-05-03 | — | — | EP | disclosed |
| US-5393763-A | Administering benzothiophenes such as raloxifene hydrochloride | ELI LILLY AND COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0635264-A2 | Antiestrogens as hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-01-25 | — | — | EP | disclosed |
| EP-0605193-A1 | Use of benzothiophenes for treatment of hypercholesterolaemia | ELI LILLY AND COMPANY (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0584952-A1 | Improvements in or relating to benzothiophenes | ELI LILLY AND COMPANY (US) | 1994-03-02 | — | — | EP | disclosed |