Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | QSOX1 | O00391 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164653 | 0.94 | F10 (0.48) | F10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5165418 | 0.92 | F10 (0.51) | F10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5165871 | 0.91 | F10 (0.50) | F10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5164723 | 0.91 | F10 (0.50) | F10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5164522 | 0.91 | F10 (0.50) | F10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5166247 | 0.90 | F10 (0.61) | F10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5166567 | 0.90 | F10 (0.61) | F10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5166188 | 0.89 | F10 (0.61) | F10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5163878 | 0.89 | F10 (0.53) | F10SMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL5164660 | 0.88 | F10 (0.47) | F10SMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351938-B1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-04-11 | — | — | EP | claimed |
| US-20040087582-A1 | Phenyl derivatives | MERCK PATENT GESELLSCHAFT (DE) | 2004-05-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087582-A1 | Phenyl derivatives | F2, F11, SERPINC1 | F10 6/4885SMN1; SMN2 3430/4885NPC1 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.