SCHEMBL516480

SCHEMBL516480

CCCCCN(C)CCCCC

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 3/20 0.61
S1PR2 O95136 1/20 0.56
S1PR1 P21453 1/20 0.56
S1PR3 Q99500 1/20 0.56
S1PR5 Q9H228 1/20 0.56
GGPS1 O95749 4/20 0.50
CHRM2 P08172 1/20 0.50
FDPS P14324 1/20 0.50
AGTR1 P30556 1/20 0.50
OPRM1 P35372 1/20 0.50
PDE3A Q14432 1/20 0.50
KDM5A P29375 4/20 0.47
KDM4C Q9H3R0 3/20 0.47
TSHR P16473 1/20 0.47
THRB P10828 1/20 0.47
KDM5C P41229 1/20 0.47
KDM5B Q9UGL1 1/20 0.47
PHF8 Q9UPP1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16790931 1.00 DNM1 (0.61) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL408903 0.97 DNM1 (0.67) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL20746425 0.97 DNM1 (0.67) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL9304444 0.97 DNM1 (0.67) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL23767361 0.97 DNM1 (0.58) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL23767359 0.97 DNM1 (0.58) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL25463105 0.97 DNM1 (0.67) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL24103978 0.97 DNM1 (0.67) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL20746523 0.97 DNM1 (0.67) DNM1S1PR2S1PR1S1PR3S1PR5
SCHEMBL23767401 0.97 DNM1 (0.58) DNM1S1PR2S1PR1S1PR3S1PR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1073 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119178832-A Gas chromatography for determining amine impurities in ibandronate sodium 石家庄凯达生物工程有限公司 2024-12-24 CN claimed
CN-116178219-B Chiral diarylmethylamine compound and preparation method thereof 上海工程技术大学 2024-06-28 CN claimed
CN-115991633-B Method for preparing methanol and ethylene glycol and co-producing formic acid by photocatalysis of polyalcohol 中国科学院大连化学物理研究所 2024-06-25 CN claimed
CN-116554119-A Enantioselective reduction (hetero) arylation method of cobalt-catalyzed cyclic N-sulfonyl imine and application 上海毕得医药科技股份有限公司 2023-08-08 CN claimed
CN-116178219-A Chiral diarylmethylamine compound and preparation method thereof 上海工程技术大学 2023-05-30 CN claimed
CN-115991633-A Method for preparing methanol and ethylene glycol and co-producing formic acid by photocatalysis of polyalcohol 中国科学院大连化学物理研究所 2023-04-21 CN claimed
CN-114702457-A Green synthesis method of diarylmethylamine compound 青岛科技大学 2022-07-05 CN claimed
US-11161861-B2 Boron-nitrogen ligand with chiral 1,2-ethylenediamine backbone, and preparation method and use thereof Lanzhou Institute of Chemical Physics, Chinese Academy of Science (CN) 2021-11-02 US claimed
US-20210253606-A1 BORON-NITROGEN LIGAND WITH CHIRAL 1,2-ETHYLENEDIAMINE BACKBONE, AND PREPARATION METHOD AND USE THEREOF SUZHOU RESEARCH INSTITUTE, LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2021-08-19 US claimed
US-11021499-B2 Bis(6-methyl-3-sulphophenyl)(2-methylphenyl)phosphine, ammonium salt thereof, and method for producing same KURARAY CO., LTD. (JP) 2021-06-01 US claimed
US-20140336343-A1 Method Of Preparing Acrylic Polymers And Products Produced Thereby LUBRIZOL ADVANCED MATERIALS, INC. 2014-11-13 US claimed
EP-2794672-A1 METHOD OF PREPARING ACRYLIC POLYMERS AND PRODUCTS PRODUCED THEREBY Lubrizol Advanced Materials, Inc. (US) 2014-10-29 EP claimed
WO-2013096206-A1 METHOD OF PREPARING ACRYLIC POLYMERS AND PRODUCTS PRODUCED THEREBY LUBRIZOL ADVANCED MATERIALS, INC. (US) 2013-06-27 WO claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
US-6080857-A CONTACTING AN AMINE NUCLEOPHILE WITH AN A,B-UNSATURATED AMIDE DERIVATIVE SUCH AS ACYL UREA, OR CARBOXYLIC IMIDE IN THE PRESENCE OF A CHIRAL LEWIS ACID COMPLEX OF A CHIRAL BISOXAZOLINYLMETHANE WITH AN AZOPHILIC METACATION SALT NORTH DAKOTA STATE UNIVERSITY (US) 2000-06-27 US claimed
US-5498772-A SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER MITSUBISHI PAPER MILLS LIMITED (JP) 1996-03-12 US claimed
EP-0222839-A4 ANTIMALARIAL COMPOUNDS. UNIV AUSTRALIAN (AU) 1988-11-09 EP claimed
EP-0222839-A1 ANTIMALARIAL COMPOUNDS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1987-05-27 EP claimed
WO-1986006718-A1 ANTIMALARIAL COMPOUNDS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1986-11-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210253606-A1 BORON-NITROGEN LIGAND WITH CHIRAL 1,2-ETHYLENEDIAMINE BACKBONE, AND PREPARATION METHOD AND USE THEREOF C3AR1, BDKRB1, BDKRB2 DNM1 2558/4885S1PR2 685/4885S1PR1 741/4885
US-11161861-B2 Boron-nitrogen ligand with chiral 1,2-ethylenediamine backbone, and preparation method and use thereof C3AR1, BDKRB1, BDKRB2 DNM1 2558/4885S1PR2 685/4885S1PR1 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.