SCHEMBL5164850

SCHEMBL5164850

NCc1cccc(N[C@H](C(=O)Nc2ccc(N3CCCCCC3=O)c(F)c2)c2ccccc2)c1

nearest known ligand 0.55

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.55
TPSAB1 Q15661 1/20 0.41
TPSD1 Q9BZJ3 1/20 0.41
TPSG1 Q9NRR2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5163726 0.99 F10 (0.56) F10TPSAB1TPSD1TPSG1
SCHEMBL5164181 0.93 F10 (0.49) F10TPSAB1TPSD1TPSG1
SCHEMBL5164036 0.91 F10 (0.45) F10TPSAB1TPSD1TPSG1
SCHEMBL5166239 0.90 F10 (0.55) F10TPSAB1TPSD1TPSG1
SCHEMBL5166110 0.90 F10 (0.46) F10TPSAB1TPSD1TPSG1
SCHEMBL5167174 0.90 F10 (0.55) F10TPSAB1TPSD1TPSG1
Hydrochloric Acid SCHEMBL28750046 0.89 F10 (0.45) F10TPSAB1TPSD1TPSG1
SCHEMBL5167014 0.89 F10 (0.56) F10TPSAB1TPSD1TPSG1
SCHEMBL5165361 0.89 F10 (0.56) F10TPSAB1TPSD1TPSG1
SCHEMBL5166370 0.89 F10 (0.54) F10TPSAB1TPSD1TPSG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7273867-B2 Phenyl derivatives MERCK PATENT GMBH (DE) 2007-09-25 US claimed
EP-1351938-B1 PHENYL DERIVATIVES MERCK PATENT GMBH (DE) 2007-04-11 EP claimed
US-20040087582-A1 Phenyl derivatives MERCK PATENT GESELLSCHAFT (DE) 2004-05-06 US claimed
US-7273867-B2 Phenyl derivatives MERCK PATENT GMBH (DE) 2007-09-25 US disclosed
EP-1351938-B1 PHENYL DERIVATIVES MERCK PATENT GMBH (DE) 2007-04-11 EP disclosed
US-20040087582-A1 Phenyl derivatives MERCK PATENT GESELLSCHAFT (DE) 2004-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040087582-A1 Phenyl derivatives F2, F11, SERPINC1 F10 6/4885TPSAB1 56/4885TPSD1 101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.