SCHEMBL5164997

SCHEMBL5164997

C=Cn1ccnc1C.COS(=O)(=O)O

nearest known ligand 0.38

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 2/20 0.34
RECQL P46063 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
HTT P42858 1/20 0.33
GAA P10253 2/20 0.33
KMT2A Q03164 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5163410 0.85 KDM4E (0.34) LMNATDP1ALDH1A1SMN1; SMN2GAA
SCHEMBL36575 0.82
Hydrochloric Acid SCHEMBL1007846 0.80
Acrylic Acid Methyl Ester SCHEMBL15637879 0.79 TDP1 (0.37) LMNATDP1ALDH1A1RECQLSMN1; SMN2
SCHEMBL2993385 0.76 RECQL (0.37) ALDH1A1RECQLSMN1; SMN2HTTKMT2A
SCHEMBL28815407 0.75 LMNA (0.44) LMNATDP1ALDH1A1SMN1; SMN2GAA
Acrylic Acid SCHEMBL11792959 0.73 LMNA (0.37) LMNATDP1ALDH1A1SMN1; SMN2GAA
Sulfuric Acid SCHEMBL21143270 0.73 LMNA (0.42) LMNATDP1SMN1; SMN2GAACYP3A4
SCHEMBL22832296 0.72 KMT2A (0.46) ALDH1A1KMT2ACA12CA1CA2
SCHEMBL3332537 0.70 TDP1 (0.43) LMNATDP1ALDH1A1SMN1; SMN2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113677318-B Increasing the stability of agents for treating keratin materials 汉高股份有限及两合公司 2024-07-09 CN disclosed
CN-117597102-A Sun protection W/O emulsion 莱雅公司 2024-02-23 CN disclosed
CN-117177732-A Comprising the use of organic C 1 -C 6 Alkoxysilane, dyeing compound and method for dyeing heat-treated keratin materials 汉高股份有限及两合公司 2023-12-05 CN disclosed
CN-116940328-A A method for dyeing keratin materials, which comprises using an organosilicon compound, a dyeing compound, a sealant and a pretreatment agent 汉高股份有限及两合公司 2023-10-24 CN disclosed
CN-116322623-A Method for dyeing keratin materials comprising the use of an organosilicon compound, a colouring compound, a sealant and a pretreatment agent 汉高股份有限及两合公司 2023-06-23 CN disclosed
CN-116157112-A Process for dyeing keratin materials comprising the use of an organosilicon compound, a phosphate and a colouring agent compound 汉高股份有限及两合公司 2023-05-23 CN disclosed
CN-111629707-A Method and device for dyeing hair fibres using radio-frequency electromagnetic radiation 洁美来有限公司 2020-09-04 CN disclosed
EP-1259672-B1 CREASE RESISTANT FINISHING OF CELLULOSE-CONTAINING TEXTILES, AND LAUNDRY POST-TREATMENT AGENTS BASF AG (DE) 2007-03-21 EP disclosed
US-20060116470-A1 Production of aqueous dispersions of cationic homo-and copolymers using amphoteric protective colloids BASF AKTIENGESELLSCHAFT (DE) 2006-06-01 US disclosed
EP-1546224-B1 THE PRODUCTION OF AQUEOUS DISPERSIONS OF CATIONIC HOMO- AND COPOLYMERS USING AMPHOTERIC PROTECTIVE COLLOIDS BASF AG (DE) 2006-05-17 EP disclosed
US-20050265950-A1 Cross-linked cationic copolymers comprising regulators, and use therof in cosmetic preparations for hair BASF AKTIENGESELLSCHAFT (DE) 2005-12-01 US disclosed
EP-1546224-A1 THE PRODUCTION OF AQUEOUS DISPERSIONS OF CATIONIC HOMO- AND COPOLYMERS USING AMPHOTERIC PROTECTIVE COLLOIDS BASF AKTIENGESELLSCHAFT (DE) 2005-06-29 EP disclosed
WO-2004022615-A1 THE PRODUCTION OF AQUEOUS DISPERSIONS OF CATIONIC HOMO- AND COPOLYMERS USING AMPHOTERIC PROTECTIVE COLLOIDS BASF AKTIENGESELLSCHAFT (DE) 2004-03-18 WO disclosed
EP-1396508-A1 The production of aqueous dispersions of cationic homo- and copolymers using amphoteric protective colloids BASF AKTIENGESELLSCHAFT (DE) 2004-03-10 EP disclosed
US-20030092804-A1 Crease resistant finishing of cellulose-containing textiles, and laundry post-treatment agents BASF AKTIENGESELLSCHAFT (DE) 2003-05-15 US disclosed
EP-1259672-A1 CREASE RESISTANT FINISHING OF CELLULOSE-CONTAINING TEXTILES, AND LAUNDRY POST-TREATMENT AGENTS BASF AKTIENGESELLSCHAFT (DE) 2002-11-27 EP disclosed
WO-2001063036-A1 CREASE RESISTANT FINISHING OF CELLULOSE-CONTAINING TEXTILES, AND LAUNDRY POST-TREATMENT AGENTS BASF AKTIENGESELLSCHAFT (DE) 2001-08-30 WO disclosed
US-5942588-A CONTAINING POLYMERIC PROTECTIVE COLLOID COMPRISING COPOLYMER OF N-VINYLPYRROLIDONE AND N-VINYLIMIDAZOLE BASF AKTIENGESELLSCHAFT (DE) 1999-08-24 US disclosed
EP-0811091-B1 AQUEOUS ALKYL DIKETENE DISPERSIONS AND THE USE THEREOF AS SIZING AGENTS FOR PAPER BASF AG (DE) 1998-08-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050265950-A1 Cross-linked cationic copolymers comprising regulators, and use therof in cosmetic preparations for hair ETF1, MTHFD2, TWF2 LMNA 1756/4885TDP1 2747/4885ALDH1A1 2687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.