Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.70 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.70 |
| ▸ | F2 | P00734 | 3/20 | 0.58 |
| ▸ | F9 | P00740 | 6/20 | 0.44 |
| ▸ | PLAU | P00749 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164956 | 0.92 | F10 (0.59) | F10PRSS1F2F9PLAU | |
| SCHEMBL5164418 | 0.87 | F10 (0.54) | F10PRSS1F2F9PLAU | |
| SCHEMBL5163975 | 0.86 | F10 (0.65) | F10PRSS1F2F9PLAU | |
| SCHEMBL5164221 | 0.86 | F10 (0.61) | F10PRSS1F2F9 | |
| SCHEMBL5164054 | 0.85 | F10 (0.63) | F10PRSS1F2F9PLAU | |
| SCHEMBL5163692 | 0.84 | F10 (0.67) | F10PRSS1F2F9PLAU | |
| SCHEMBL5163529 | 0.84 | F10 (0.51) | F10PRSS1F2F9PLAU | |
| SCHEMBL5164065 | 0.83 | F10 (0.68) | F10PRSS1F2F9PLAU | |
| SCHEMBL5165461 | 0.82 | F10 (0.77) | F10PRSS1F2KMT2ASMN1; SMN2 | |
| SCHEMBL5164062 | 0.81 | F10 (0.69) | F10PRSS1F2F9PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273867-B2 | Phenyl derivatives | MERCK PATENT GMBH (DE) | 2007-09-25 | — | — | US | claimed |
| EP-1351938-B1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-04-11 | — | — | EP | claimed |
| US-20040087582-A1 | Phenyl derivatives | MERCK PATENT GESELLSCHAFT (DE) | 2004-05-06 | — | — | US | claimed |
| US-7273867-B2 | Phenyl derivatives | MERCK PATENT GMBH (DE) | 2007-09-25 | — | — | US | disclosed |
| EP-1351938-B1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2007-04-11 | — | — | EP | disclosed |
| US-20040087582-A1 | Phenyl derivatives | MERCK PATENT GESELLSCHAFT (DE) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087582-A1 | Phenyl derivatives | F2, F11, SERPINC1 | F10 6/4885PRSS1 88/4885F2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.