SCHEMBL5165582

SCHEMBL5165582

CCCCCCCCCCCCc1ccc(OC(=O)Oc2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.62
THRA P10827 1/20 0.62
ALDH1A1 P00352 3/20 0.54
RARB P10826 5/20 0.53
MEN1 O00255 1/20 0.53
RARA P10276 1/20 0.53
MAPT P10636 1/20 0.53
MTOR P42345 1/20 0.53
KMT2A Q03164 1/20 0.53
PPARG P37231 1/20 0.52
PPARA Q07869 1/20 0.52
FAAH O00519 5/20 0.51
ESR1 P03372 2/20 0.50
ADRA2A P08913 2/20 0.50
ADORA3 P0DMS8 2/20 0.50
TACR2 P21452 2/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 2/20 0.50
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247206 1.00 THRB (0.62) THRBTHRAALDH1A1RARBMEN1
SCHEMBL249214 1.00 THRB (0.62) THRBTHRAALDH1A1RARBMEN1
SCHEMBL5166821 1.00 THRB (0.62) THRBTHRAALDH1A1RARBMEN1
SCHEMBL248390 0.98 THRB (0.63) THRBTHRAALDH1A1RARBMEN1
Bicarbonate SCHEMBL27833282 0.94 THRB (0.66) THRBTHRAALDH1A1RARBMEN1
Bicarbonate SCHEMBL27833327 0.94 THRB (0.66) THRBTHRAALDH1A1RARBMEN1
SCHEMBL247374 0.94 THRB (0.56) THRBTHRAALDH1A1RARBFAAH
SCHEMBL17473027 0.94 THRB (0.69) THRBTHRAALDH1A1RARBMEN1
SCHEMBL1836715 0.94 THRB (0.69) THRBTHRAALDH1A1RARBMEN1
SCHEMBL1834795 0.94 THRB (0.69) THRBTHRAALDH1A1RARBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1436343-B8 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GEN ELECTRIC (US) 2007-04-11 EP disclosed
CN-1308370-C Method for end-capping polycarbonate resins and composition for use in same GEN ELECTRIC (US) 2007-04-04 CN disclosed
EP-1436343-B1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GEN ELECTRIC COMPANY A CORP OF (US) 2006-11-02 EP disclosed
CN-1646599-A Method for end-capping polycarbonate resins and compositions useful therein GEN ELECTRIC (US) 2005-07-27 CN disclosed
EP-1436343-A1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME General Electric Company A Corporation of the State of New York (US) 2004-07-14 EP disclosed
WO-2003031497-A1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GENERAL ELECTRIC COMPANY (US) 2003-04-17 WO disclosed
US-6500914-B1 MELT TRANSESTERIFICATION OF FREE HYDROXYL TERMINAL GROUPS WITH A DIARYL CARBONATE GENERAL ELECTRIC COMPANY 2002-12-31 US disclosed