SCHEMBL247374

SCHEMBL247374

CCCCc1ccc(OC(=O)Oc2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.56
ALDH1A1 P00352 2/20 0.54
HPGD P15428 1/20 0.54
HSD17B10 Q99714 1/20 0.54
THRA P10827 1/20 0.54
TRPV1 Q8NER1 1/20 0.51
RARB P10826 1/20 0.50
FFAR1 O14842 2/20 0.47
PLK1 P53350 1/20 0.46
FAAH O00519 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL248390 0.95 THRB (0.63) THRBALDH1A1HPGDHSD17B10THRA
SCHEMBL5165582 0.94 THRB (0.62) THRBALDH1A1HSD17B10THRARARB
SCHEMBL247206 0.94 THRB (0.62) THRBALDH1A1HSD17B10THRARARB
SCHEMBL5166821 0.94 THRB (0.62) THRBALDH1A1HSD17B10THRARARB
SCHEMBL249214 0.94 THRB (0.62) THRBALDH1A1HSD17B10THRARARB
SCHEMBL233924 0.93 THRB (0.63) THRBALDH1A1HPGDHSD17B10THRA
SCHEMBL17473054 0.92 RARB (0.58) THRBALDH1A1HPGDHSD17B10THRA
SCHEMBL10706439 0.90 THRB (0.69) THRBALDH1A1HPGDHSD17B10THRA
SCHEMBL10708974 0.90 THRB (0.60) THRBALDH1A1HPGDHSD17B10THRA
SCHEMBL360649 0.90 THRB (0.60) THRBALDH1A1THRAFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 279 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures COVESTRO DEUTSCHLAND AG (DE) 2026-04-14 US disclosed
EP-3055342-B1 PROCESS FOR PREPARING POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES USING A SALT OF A WEAK ACID COVESTRO DEUTSCHLAND AG (DE) 2026-03-04 EP disclosed
US-12365775-B2 Process for partial colouring of plastic parts using solid colourants in colour- carrier layers COVESTRO DEUTSCHLAND AG (DE) 2025-07-22 US disclosed
US-20250205963-A1 METHOD FOR PRODUCING A PLASTIC MOLDING tooz technologies GmbH (DE) 2025-06-26 US disclosed
EP-4549163-A2 IMPROVED METHOD FOR PARTIAL COLOURING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2025-05-07 EP disclosed
EP-2593288-B2 APPARATUS AND PROCESS FOR PRODUCING PRODUCTS FROM PIGMENT-CONTAINING POLYMER MIXTURES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2025-04-16 EP disclosed
US-20250091332-A1 FILM STRUCTURE SUITABLE FOR RAPID LAMINATION COVESTRO DEUTSCHLAND AG (DE) 2025-03-20 US disclosed
EP-3055344-B1 POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES COVESTRO DEUTSCHLAND AG (DE) 2025-03-12 EP disclosed
EP-3840958-B1 IMPROVED METHOD FOR PARTIAL COLOURING OF PLASTIC PARTS COVESTRO DEUTSCHLAND AG (DE) 2025-02-19 EP disclosed
EP-4493388-A1 METHOD FOR PRODUCING A PLASTIC MOLDING tooz technologies GmbH (DE) 2025-01-22 EP disclosed
US-20040127677-A1 Polycarbonates, polyester carbonates and polyesters having lateral, cycloalkyl-substituted phenols BAYER AKTIENGESELLSCHAFT (DE) 2004-07-01 US disclosed
US-6753405-B2 MORE THAN 35 MOLE % OF UNITS DERIVED FROM DIHYDROXYDIPHENYLENE AND THE REST FROM AN ALKYLIDENE OR CYCLOALKYLIDENE BISPHENOL; PREPARED BY MELT TRANSESTERIFICATION; USED TO PREPARE TRANSPARENT MOLDINGS BAYER AKTIENGESELLSCHAFT (DE) 2004-06-22 US disclosed
US-20040103717-A1 Process for the production of polycarbonate which is damaged to a particularly small extent by oxygen BAYER AKTIENGESELLSCHAFT (DE) 2004-06-03 US disclosed
EP-1412411-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-04-28 EP disclosed
US-6620902-B2 Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing GENERAL ELECTRIC COMPANY 2003-09-16 US disclosed
US-20030088051-A1 Process for preparing polycarbonate and apparatus for preparing polycarbonate GENERAL ELECTRIC COMPANY 2003-05-08 US disclosed
US-20030055201-A1 Process for optimising the production of polycarbonate by melt transesterification BAYER AKTIENGESELLSCHAFT (DE) 2003-03-20 US disclosed
US-20030027971-A1 Preparation of copolycarbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed
WO-2003008481-A2 PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-01-30 WO disclosed
US-20020137874-A1 Process for producing oligocarbonates COVESTRO DEUTSCHLAND AG (DE) 2002-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures ASH2L, SMC2, ELL THRB 3930/4885ALDH1A1 4181/4885HPGD 4856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.