Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK2 | P53671 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3559157 | 0.84 | GFER (0.56) | LIMK2KMT2AMEN1MAPTGFER | |
| SCHEMBL3553957 | 0.84 | TSHR (0.53) | ARKMT2AMEN1SLC16A3GPR55 | |
| SCHEMBL3564489 | 0.81 | GFER (0.60) | LIMK2KMT2AMEN1MAPTGFER | |
| SCHEMBL5162154 | 0.78 | SLC16A3 (0.51) | SLC16A3TAS2R14 | |
| SCHEMBL3560145 | 0.76 | MEN1 (0.51) | LIMK2ARKMT2AMEN1MAPT | |
| SCHEMBL3558574 | 0.76 | CACNA1H (0.48) | LIMK2TDP1WDR5LMNASLC16A3 | |
| SCHEMBL3555158 | 0.76 | CA12 (0.53) | KMT2AMEN1MAPTGFERWDR5 | |
| SCHEMBL3564080 | 0.76 | ALDH1A1 (0.63) | KMT2AMEN1MAPTGFERTDP1 | |
| SCHEMBL3555752 | 0.75 | TSHR (0.56) | KMT2ASLC16A3POLBHTT | |
| SCHEMBL5162168 | 0.74 | HDAC3 (0.42) | KMT2ALMNASLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761486-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | Merck Patent GmbH (DE) | 2007-03-14 | — | — | EP | claimed |
| WO-2006000288-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | claimed |