Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 9/20 | 0.44 |
| ▸ | SGMS1 | Q86VZ5 | 5/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10677667 | 0.88 | KMT2A (0.71) | HDAC4PGRMEN1KMT2ASRC | |
| SCHEMBL5166291 | 0.85 | HDAC4 (0.58) | HDAC4PGRMEN1KMT2ASRC | |
| SCHEMBL5164782 | 0.85 | HDAC4 (0.58) | HDAC4PGRMEN1KMT2ASRC | |
| SCHEMBL5163615 | 0.85 | HDAC4 (0.58) | HDAC4PGRMEN1KMT2ASRC | |
| SCHEMBL10674517 | 0.77 | MEN1 (0.68) | PGRMEN1KMT2ASRCALDH1A1 | |
| SCHEMBL10677325 | 0.76 | MEN1 (0.49) | PGRMEN1KMT2ASRCALDH1A1 | |
| SCHEMBL10670287 | 0.76 | MEN1 (0.78) | HDAC4PGRMEN1KMT2ASRC | |
| SCHEMBL10671773 | 0.75 | MEN1 (0.54) | PGRMEN1KMT2ASRC | |
| SCHEMBL14376051 | 0.75 | HDAC4 (0.78) | HDAC4PGRMEN1KMT2ASRC | |
| SCHEMBL10671530 | 0.74 | MEN1 (0.55) | HDAC4PGRMEN1KMT2ASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224172-B1 | DRUGS FOR THE TREATMENT OF MALIGNANT TUMOURS | ACTIVE BIOTECH AB (SE) | 2007-04-04 | — | — | EP | disclosed |
| US-6395750-B1 | Includes laquinimod, N-ethyl-N-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxo-quinoline-3-carboxamide and its salts; breat or prostate cancer | ACTIVE BIOTECH AB (SE) | 2002-05-28 | — | — | US | disclosed |