Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14731146 | 0.88 | TSHR (0.40) | EGFRHPGDTSHRMAPTALDH1A1 | |
| SCHEMBL15316683 | 0.84 | TDP1 (0.43) | EGFRHPGDTSHRHTR2ASLC6A4 | |
| SCHEMBL12798326 | 0.84 | EGFR (0.40) | EGFRHPGDTSHRMAPTALDH1A1 | |
| SCHEMBL23364293 | 0.80 | KDM4E (0.44) | TSHRMAPTALDH1A1HTTKMT2A | |
| SCHEMBL9448834 | 0.79 | EGFR (0.39) | EGFRTSHRMAPTALDH1A1HTT | |
| SCHEMBL901666 | 0.77 | HSD17B10 (0.41) | EGFRTSHRSLC6A4KCNH2ALDH1A1 | |
| SCHEMBL25540658 | 0.77 | CA1 (0.47) | TSHRMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL43286 | 0.75 | GABRA1 (0.44) | HPGDTSHRHTR2ASLC6A4KCNH2 | |
| SCHEMBL29426994 | 0.75 | GABRA1 (0.44) | HPGDTSHRHTR2ASLC6A4KCNH2 | |
| SCHEMBL18304415 | 0.75 | PYCR1 (0.39) | EGFRTSHRMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417032-B2 | D-xylopyranosyl-phenyl-substituted cycles, medicaments containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-26 | — | — | US | disclosed |
| US-7417032-B2 | D-xylopyranosyl-phenyl-substituted cycles, medicaments containing such compounds, their use and process for their manufacture | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-26 | — | — | US | disclosed |
| EP-1773800-A1 | D-GLUCOPYRANOSYL PHENYL-SUBSTITUTED CYCLENE, MEDICAMENTS CONTAINING THESE COMPOUNDS, THEIR USE, AND METHOD FOR THE PRODUCTION THEREOF | Boehringer Ingelheim International GmbH (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006010557-A1 | D-GLUCOPYRANOSYL PHENYL-SUBSTITUTED CYCLENE, MEDICAMENTS CONTAINING THESE COMPOUNDS, THEIR USE, AND METHOD FOR THE PRODUCTION THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-02-02 | — | — | WO | disclosed |