Isobutylbenzene

Isobutylbenzene

SCHEMBL5166156

CC(C)Cc1ccccc1.N=C=O.N=C=O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.50
SLC6A2 P23975 2/20 0.50
SIGMAR1 Q99720 2/20 0.50
MAOA P21397 1/20 0.50
SLC6A4 P31645 1/20 0.50
SLC6A3 Q01959 1/20 0.50
CYP2A6 P11509 1/20 0.50
ADORA2A P29274 1/20 0.50
ADORA1 P30542 1/20 0.50
SLC18A2 Q05940 1/20 0.47
CYP2D6 P10635 1/20 0.47
PTGS1 P23219 3/20 0.46
PTGS2 P35354 3/20 0.46
LMNA P02545 2/20 0.46
CYP2C9 P11712 2/20 0.46
AKR1C3 P42330 2/20 0.46
CXCR1 P25024 2/20 0.46
CXCR2 P25025 2/20 0.46
ALOX5 P09917 2/20 0.46
ALB P02768 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isobutylbenzene SCHEMBL28150610 1.00 TAAR1 (0.50) TAAR1SLC6A2SIGMAR1MAOASLC6A4
Isobutylbenzene SCHEMBL2571645 0.86 SIGMAR1 (0.64) TAAR1SLC6A2SIGMAR1MAOASLC6A4
Isobutylbenzene SCHEMBL57393 0.86 SIGMAR1 (0.64) TAAR1SLC6A2SIGMAR1MAOASLC6A4
Isobutylbenzene SCHEMBL7493657 0.86 SIGMAR1 (0.64) TAAR1SLC6A2SIGMAR1MAOASLC6A4
Isobutylbenzene SCHEMBL27343561 0.84 TAAR1 (0.56) TAAR1SLC6A2SIGMAR1MAOASLC6A4
Isobutylbenzene SCHEMBL28231782 0.84 TAAR1 (0.56) TAAR1SLC6A2SIGMAR1MAOASLC6A4
Isobutylbenzene SCHEMBL6891614 0.84 SIGMAR1 (0.61) TAAR1SLC6A2SIGMAR1MAOASLC6A4
Isobutylbenzene SCHEMBL31284788 0.84 SIGMAR1 (0.61) TAAR1SLC6A2SIGMAR1MAOASLC6A4
Isobutylbenzene SCHEMBL31498540 0.84 SIGMAR1 (0.61) TAAR1SLC6A2SIGMAR1MAOASLC6A4
Isobutylbenzene SCHEMBL11468970 0.84 TAAR1 (0.61) TAAR1SLC6A2SIGMAR1MAOASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116997464-A Glass laminate article and adhesive composition therefor 康宁股份有限公司 2023-11-03 CN disclosed
CN-109563269-B Aromatic polythiol compound for optical material SKC株式会社 2021-07-23 CN disclosed
EP-1155418-B1 MEDICAL TOOLS AND DEVICES WITH IMPROVED ULTRASOUND VISIBILITY GE HEALTHCARE LTD (GB) 2007-04-11 EP disclosed