SCHEMBL5166278

SCHEMBL5166278

Nc1scc2c1OCCO2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BAZ2B Q9UIF8 1/20 0.44
HTT P42858 4/20 0.41
HPGD P15428 1/20 0.41
NCOA1 Q15788 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
TSHR P16473 2/20 0.40
CHEK1 O14757 3/20 0.35
CHEK2 O96017 3/20 0.35
ALDH1A1 P00352 3/20 0.35
MAPT P10636 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
TP53 P04637 1/20 0.35
GAA P10253 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL880222 0.76 BAZ2B (0.47) BAZ2BHTTHPGDNCOA1NCOA3
SCHEMBL19214670 0.73 BAZ2B (0.44) BAZ2BHTTHPGDNCOA1NCOA3
SCHEMBL433905 0.73 BAZ2B (0.49) BAZ2BHTTHPGDNCOA1NCOA3
SCHEMBL25694428 0.73 BAZ2B (0.44) BAZ2BHTTHPGDNCOA1NCOA3
SCHEMBL3715486 0.73 BAZ2B (0.44) BAZ2BHTTHPGDNCOA1NCOA3
SCHEMBL24762447 0.73 BAZ2B (0.44) BAZ2BHTTHPGDNCOA1NCOA3
SCHEMBL15668445 0.73 BAZ2B (0.44) BAZ2BHTTHPGDNCOA1NCOA3
SCHEMBL12414587 0.73 BAZ2B (0.44) BAZ2BHTTHPGDNCOA1NCOA3
SCHEMBL982629 0.73 BAZ2B (0.49) BAZ2BHTTHPGDNCOA1NCOA3
SCHEMBL5015667 0.72 HTT (0.41) BAZ2BHTTHPGDNCOA1NCOA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070071987-A1 Base-inhibited oxidative polymerization of thiophenes and anilines with iron (III) salts NANON A/S (DK) 2007-03-29 US claimed
CN-117596920-A Light-emitting element 三星显示有限公司 2024-02-23 CN disclosed
EP-3562810-B1 BENZHYDROXAMIC ACID DERIVATIVES AS SELECTIVE HDAC6 INHIBITORS ITALFARMACO SPA (IT) 2023-05-03 EP disclosed
US-11077098-B2 Opioid receptor ligands and methods of using and making same TREVENA, INC. (US) 2021-08-03 US disclosed
WO-2020078815-A1 INDACENO DERIVATIVES AS ORGANIC SEMICONDUCTORS BASF SE (DE) 2020-04-23 WO disclosed
WO-2017089952-A1 DEGRADABLE CONJUGATED POLYMERS The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel (US) 2017-06-01 WO disclosed
WO-2012121417-A1 CONDUCTING POLYMER / REDOX POLYMER BLENDS VIA IN-SITU OXIDATIVE POLYMERIZATION - PREPARATION METHODS AND APPLICATION AS AN ELECTRO-ACTIVE POLYMERIC MATERIALS WASEDA UNIVERSITY (JP) 2012-09-13 WO disclosed
US-20070071987-A1 Base-inhibited oxidative polymerization of thiophenes and anilines with iron (III) salts NANON A/S (DK) 2007-03-29 US disclosed
EP-1765908-A1 BASE-INHIBITED OXIDATIVE POLYMERIZATION OF THIOPHENES AND ANILINES WITH IRON (III) SALTS Nanon A/S (DK) 2007-03-28 EP disclosed
WO-2005103109-A1 BASE-INHIBITED OXIDATIVE POLYMERIZATION OF THIOPHENES AND ANILINES WITH IRON (III) SALTS WINTHER-JENSEN BJOERN (AU) 2005-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11077098-B2 Opioid receptor ligands and methods of using and making same OPRL1, OPRK1, OPRM1 BAZ2B 4599/4885HTT 1382/4885HPGD 776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.