SCHEMBL5166306

SCHEMBL5166306

CCCCOC(=O)CCN1C(=O)C=CC1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.58
ALDH1A1 P00352 2/20 0.58
MAPT P10636 2/20 0.53
RECQL P46063 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
PTGS1 P23219 7/20 0.51
PTGS2 P35354 7/20 0.51
MGLL Q99685 3/20 0.51
FAAH O00519 1/20 0.51
GAA P10253 1/20 0.50
CYP1A2 P05177 1/20 0.49
HPGD P15428 1/20 0.49
CYP2C19 P33261 1/20 0.49
BLM P54132 1/20 0.49
WRN Q14191 1/20 0.49
HIF1A Q16665 1/20 0.49
GSK3A P49840 1/20 0.47
GSK3B P49841 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5164101 0.95 MAPT (0.59) MAPK1ALDH1A1MAPTRECQLL3MBTL1
SCHEMBL15023989 0.94 MAPT (0.58) MAPK1ALDH1A1MAPTRECQLL3MBTL1
SCHEMBL15024119 0.94 MAPT (0.58) MAPK1ALDH1A1MAPTRECQLL3MBTL1
SCHEMBL15023952 0.94 MAPT (0.58) MAPK1ALDH1A1MAPTRECQLL3MBTL1
SCHEMBL5160668 0.92 MAPK1 (0.59) MAPK1ALDH1A1MAPTRECQLL3MBTL1
SCHEMBL5160607 0.90 ALDH1A1 (0.51) MAPK1ALDH1A1MAPTRECQLL3MBTL1
SCHEMBL14984834 0.90 PTGS1 (0.49) MAPK1ALDH1A1MAPTRECQLL3MBTL1
SCHEMBL5165324 0.89 PTGS1 (0.60) MAPK1ALDH1A1MAPTRECQLPTGS1
SCHEMBL5165318 0.89 PTGS1 (0.60) MAPK1ALDH1A1MAPTRECQLPTGS1
SCHEMBL5166261 0.88 PTGS1 (0.57) MAPK1ALDH1A1MAPTRECQLL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1582548-B1 PROCESS FOR PRODUCING POLYMERIZABLE POLYBRANCHED POLYESTER DAINIPPON INK & CHEMICALS (JP) 2007-03-28 EP disclosed
CN-1303130-C Process for producing polymerizable polybranched polyester DAINIPPON INK & CHEMICALS (JP) 2007-03-07 CN disclosed
US-7141642-B2 Process for producing polymerizable polybranched polyester DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-11-28 US disclosed
US-20060047140-A1 Process for producing polymerizable polybranched polyester DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-03-02 US disclosed
CN-1714113-A Process for producing polymerizable polybranched polyester DAINIPPON INK & CHEMICALS (JP) 2005-12-28 CN disclosed
EP-1582548-A1 PROCESS FOR PRODUCING POLYMERIZABLE POLYBRANCHED POLYESTER DAINIPPON INK AND CHEMICALS, INC. (JP) 2005-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047140-A1 Process for producing polymerizable polybranched polyester ACSL4, ACSL1, HACL2 MAPK1 4025/4885ALDH1A1 1751/4885MAPT 3337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.