Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.87 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.87 |
| ▸ | TSHR | P16473 | 1/20 | 0.87 |
| ▸ | BLM | P54132 | 1/20 | 0.87 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.85 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.85 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Picotamide SCHEMBL30206880 | 0.93 | CYP1A2 (1.00) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| Picotamide SCHEMBL137025 | 0.93 | CYP1A2 (1.00) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| Picotamide SCHEMBL30254057 | 0.93 | CYP1A2 (1.00) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| Picotamide SCHEMBL4877561 | 0.92 | CYP1A2 (0.98) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| Picotamide SCHEMBL2916058 | 0.92 | L3MBTL1 (1.00) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| Picotamide SCHEMBL4206054 | 0.92 | CYP1A2 (0.98) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| SCHEMBL5170370 | 0.91 | CYP1A2 (0.87) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| Picotamide SCHEMBL4869999 | 0.90 | CYP1A2 (0.93) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| Picotamide SCHEMBL4875206 | 0.90 | CYP1A2 (0.93) | CYP1A2CYP3A4TSHRBLML3MBTL1 | |
| Picotamide SCHEMBL4877894 | 0.89 | CYP1A2 (0.91) | CYP1A2CYP3A4TSHRBLML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270558-B1 | \"Compound for the treatment of atherosclerotic-thrombotic pathological conditions\ | CASAGRANDE CESARE (IT) | 2007-04-25 | — | — | EP | disclosed |
| US-6525078-B1 | Compound for the treatment of atherosclerotic-thrombotic pathological conditions | CASAGRANDE CESARE (IT) | 2003-02-25 | — | — | US | disclosed |
| EP-1270558-A1 | \"Compound for the treatment of atherosclerotic-thrombotic pathological conditions\ | Casagrande, Cesare (IT) | 2003-01-02 | — | — | EP | disclosed |