Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 11/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5165321 | 0.99 | OPRM1 (0.47) | OPRM1OPRL1CXCR3 | |
| SCHEMBL5163788 | 0.80 | OPRL1 (0.53) | OPRM1OPRL1CXCR3 | |
| SCHEMBL5168924 | 0.80 | OPRM1 (0.54) | OPRM1OPRL1SLC6A4 | |
| Hydrochloric Acid SCHEMBL5165885 | 0.79 | OPRL1 (0.54) | OPRM1OPRL1CXCR3 | |
| Hydrochloric Acid SCHEMBL5165622 | 0.79 | OPRM1 (0.52) | OPRM1OPRL1SLC6A4 | |
| SCHEMBL5166917 | 0.74 | OPRL1 (0.51) | OPRM1OPRL1SLC6A4 | |
| Hydrochloric Acid SCHEMBL5163924 | 0.73 | OPRL1 (0.50) | OPRM1OPRL1 | |
| SCHEMBL4076511 | 0.73 | OPRL1 (0.59) | OPRM1OPRL1SLC6A4 | |
| SCHEMBL20866603 | 0.73 | OPRL1 (0.59) | OPRM1OPRL1 | |
| SCHEMBL21766654 | 0.70 | OPRM1 (0.52) | OPRM1OPRL1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392641-B1 | SUBSTITUTED CYCLOHEXANE-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2007-04-11 | — | — | EP | claimed |