Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSH | P09668 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16177752 | 0.72 | BCHE (0.39) | CETPCNR2CTSLPTGESALOX5 | |
| SCHEMBL292351 | 0.72 | CETP (0.41) | CETPCNR2CTSLPTGESALOX5 | |
| SCHEMBL30524953 | 0.72 | CETP (0.42) | CETPCNR2CTSLPTGESALOX5 | |
| SCHEMBL10452494 | 0.72 | CTSK (0.45) | CETPCNR2CTSLCTSKCTSB | |
| SCHEMBL6675434 | 0.71 | CETP (0.40) | CETPCNR2CTRC | |
| SCHEMBL11733830 | 0.71 | CETP (0.40) | CETPCNR2CTRC | |
| SCHEMBL6679829 | 0.71 | CTSK (0.43) | CETPCNR2CTSLPTGESALOX5 | |
| SCHEMBL6678199 | 0.70 | CETP (0.42) | CETPCNR2CTRC | |
| SCHEMBL21230427 | 0.69 | CTSK (0.43) | CETPCNR2CTRCCTSLPTGES | |
| SCHEMBL3338742 | 0.69 | CETP (0.44) | CETPCNR2CTSLPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183367-B2 | Vinyl sulphone modified polymer | N.V. ORGANON (NL) | 2007-02-27 | — | — | US | disclosed |
| US-20040186256-A1 | Vinyl sulphone modified polymer | MERCK SHARP & DOHME B.V. (NL) | 2004-09-23 | — | — | US | disclosed |
| EP-1001997-B1 | VINYL SULPHONE MODIFIED POLYMER | AKZO NOBEL NV (NL) | 2003-03-26 | — | — | EP | disclosed |
| EP-1001997-A1 | VINYL SULPHONE MODIFIED POLYMER | Akzo Nobel N.V. (NL) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999007751-A1 | VINYL SULPHONE MODIFIED POLYMER | AKZO NOBEL N.V. (NL) | 1999-02-18 | — | — | WO | disclosed |