Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSH | P09668 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683665 | 0.95 | ALDH1A1 (0.47) | CETPCNR2ALDH1A1TSHRCYP3A4 | |
| SCHEMBL6685008 | 0.93 | ALDH1A1 (0.49) | CETPCNR2ALDH1A1MAPK1CSNK1E | |
| SCHEMBL27277461 | 0.93 | ALDH1A1 (0.49) | CETPCNR2ALDH1A1MAPK1CSNK1E | |
| SCHEMBL31470624 | 0.93 | ALDH1A1 (0.49) | CETPCNR2ALDH1A1MAPK1CSNK1E | |
| SCHEMBL7850044 | 0.89 | TSHR (0.43) | TSHRPPARGMAPT | |
| SCHEMBL10245222 | 0.89 | TSHR (0.43) | TSHRPPARGMAPT | |
| SCHEMBL31354637 | 0.85 | CTRC (0.42) | CETPALDH1A1TSHRCYP3A4MAPK1 | |
| SCHEMBL21230427 | 0.84 | CTSK (0.43) | CTSKCTSLCTSBCETPCNR2 | |
| SCHEMBL2300063 | 0.84 | LTA4H (0.44) | ALDH1A1TSHRMAPK1TDP1MAPT | |
| SCHEMBL1014269 | 0.84 | TSHR (0.39) | ALDH1A1TSHRMAPK1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368083-A | heteroaryl compounds and their use as therapeutic agents | 东亚首希控股股份有限公司 | 2018-08-03 | — | — | CN | disclosed |
| US-9563121-B2 | Actinic ray-sensitive or radiation-sensitive resin composition, and, actinic ray-sensitive or radiation-sensitive film and pattern forming method, each using the composition | FUJIFILM CORPORATION (JP) | 2017-02-07 | — | — | US | disclosed |
| WO-2010010119-A1 | AMINO ACID SEQUENCES DIRECTED AGAINST MULTITARGET SCAVENGER RECEPTORS AND POLYPEPTIDES | ABLYNX NV (BE) | 2010-01-28 | — | — | WO | disclosed |
| EP-0985649-B1 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6462248-B1 | THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0985649-A2 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-4013640-A | SOLVENT EXTRACTION, DISTILLATION | UNION CARBIDE CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |