Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.48 |
| ▸ | FLT4 | P35916 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ESRRB | O95718 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247138 | 0.86 | SIGMAR1 (0.45) | ALDH1A1TMEM97SIGMAR1NR1H4SMN1; SMN2 | |
| SCHEMBL5165653 | 0.85 | FLT1 (0.43) | FLT1FLT4KDRALDH1A1MAPK1 | |
| SCHEMBL5182136 | 0.83 | MEN1 (0.55) | ALDH1A1TMEM97SIGMAR1NR1H4SMN1; SMN2 | |
| SCHEMBL5167511 | 0.80 | PPARG (0.49) | TMEM97SIGMAR1NR1H4SMN1; SMN2LMNA | |
| SCHEMBL5182316 | 0.80 | MAPT (0.44) | TMEM97SIGMAR1NR1H4SMN1; SMN2LMNA | |
| SCHEMBL5166698 | 0.78 | SIGMAR1 (0.51) | ALDH1A1MAPK1TMEM97SIGMAR1NR1H4 | |
| SCHEMBL5166146 | 0.76 | KMT2A (0.47) | MAPK1TMEM97SIGMAR1NR1H4SMN1; SMN2 | |
| SCHEMBL6247255 | 0.76 | ESRRG (0.55) | HIF1ATMEM97SIGMAR1NR1H4LMNA | |
| SCHEMBL9490560 | 0.76 | ALDH1A1 (0.62) | ALDH1A1MAPK1HIF1ATMEM97SIGMAR1 | |
| SCHEMBL5170410 | 0.75 | HPGD (0.48) | TMEM97SIGMAR1NR1H4LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329399-B1 | Antifungal amine derivatives and processing for producing the same | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-12-11 | — | — | US | claimed |
| EP-1020426-A1 | AMINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-07-19 | — | — | EP | claimed |
| EP-1561744-B1 | AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS ANTIMYCOTIC AGENT | POLA CHEM IND INC (JP) | 2007-04-18 | — | — | EP | disclosed |
| EP-1561744-A2 | AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS ANTIMYCOTIC AGENT | POLA CHEMICAL INDUSTRIES INC. (JP) | 2005-08-10 | — | — | EP | disclosed |
| US-6329399-B1 | Antifungal amine derivatives and processing for producing the same | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1020426-A1 | AMINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-07-19 | — | — | EP | disclosed |