Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5170531 | 0.87 | LMNA (0.50) | LMNA | |
| SCHEMBL7563683 | 0.85 | LMNA (0.48) | LMNA | |
| SCHEMBL5169305 | 0.81 | LMNA (0.40) | LMNAALDH1A1 | |
| SCHEMBL5167620 | 0.80 | ALDH1A1 (0.37) | LMNAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL441131 | 0.77 | CA1 (0.44) | ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7563021 | 0.70 | LMNA (0.43) | LMNAALDH1A1CYP2C9CYP2C19PTGS1 | |
| Water SCHEMBL27863122 | 0.70 | LMNA (0.34) | LMNA | |
| SCHEMBL24026496 | 0.69 | CYP1A2 (0.41) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19583184 | 0.69 | CYP1A2 (0.41) | LMNAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| Ethylene SCHEMBL10561761 | 0.69 | LMNA (0.38) | LMNAALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1182184-B1 | PROCESS FOR PRODUCING TETRAFLUORO BENZENECARBALDEHYDES AND TETRAFLUORO BENZENEMETHANOLS | SHOWA DENKO KK (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-6624336-B1 | Acetalization of tetrafluorobenzonitriles using alcohols, in the presence of mineral acids and metal catalysts to form chemical intermediates for nontoxic insecticides | SHOWA DENKO K.K. (JP) | 2003-09-23 | — | — | US | disclosed |
| EP-1182184-A1 | PROCESS FOR PRODUCING TETRAFLUORO BENZENEMETHANOLS | Showa Denko K K (JP) | 2002-02-27 | — | — | EP | disclosed |