⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165914 | 0.86 | CA2 (0.45) | — | |
| SCHEMBL28371689 | 0.82 | ZDHHC7 (0.48) | — | |
| SCHEMBL10304982 | 0.80 | — | — | |
| SCHEMBL10305019 | 0.80 | — | — | |
| SCHEMBL25516 | 0.80 | — | — | |
| SCHEMBL3332532 | 0.80 | — | — | |
| SCHEMBL5164694 | 0.79 | — | — | |
| SCHEMBL5167562 | 0.78 | CHRM1 (0.37) | — | |
| SCHEMBL4431247 | 0.78 | CA1 (0.47) | — | |
| SCHEMBL6053376 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779128-B | Organic semiconductor | 天光材料科技股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-105764957-B | Polycyclic polymers comprising thiophene units, method for producing such polymers and use thereof | 默克专利股份有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-107892729-A | The copolymer and manufacture method of (methyl) acrylic acid triisopropylsilyl ester and (methyl) acrylic acid derivative | 信越化学工业株式会社 | 2018-04-10 | — | — | CN | disclosed |
| EP-1772150-A1 | Benzothiophene formulations of a specific dosage | Eli Lilly & Company (US) | 2007-04-11 | — | — | EP | disclosed |
| US-20060106010-A1 | Methods for inhibiting bone loss | ELI LILLY AND COMPANY | 2006-05-18 | — | — | US | disclosed |
| US-RE39049-E1 | Methods for inhibiting bone loss | ELI LILLY AND COMPANY (US) | 2006-03-28 | — | — | US | disclosed |
| US-RE38968-E1 | Methods for inhibiting bone loss using 6-hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl-4-[2-(piperidin-1-yl) ethoxyphenylimethanone hydrochloride | ELI LILLY AND COMPANY (US) | 2006-02-07 | — | — | US | disclosed |
| US-6906086-B2 | Methods for inhibiting bone loss | ELI LILLY AND COMPANY (US) | 2005-06-14 | — | — | US | disclosed |
| EP-1438957-A1 | Benzothiophene formulations of a specific dosage | ELI LILLY AND COMPANY (US) | 2004-07-21 | — | — | EP | disclosed |
| US-20030212058-A1 | Methods for inhibiting bone loss | ELI LILLY AND COMPANY | 2003-11-13 | — | — | US | disclosed |
| US-5457117-A | Method for inhibiting bone loss using 6-hydroxy-2-(4-hydroxyphenyl)-benzo[B][2-(piperidin-1-yl)ethoxyphenylimethanone hydrochloride | ELI LILLY AND COMPANY (US) | 1995-10-10 | — | — | US | disclosed |
| US-5441964-A | Especially post-memopausal women | ELI LILLY AND COMPANY (US) | 1995-08-15 | — | — | US | disclosed |
| EP-0665015-A2 | Combination treatment for osteoporosis | ELI LILLY AND COMPANY (US) | 1995-08-02 | — | — | EP | disclosed |
| EP-0657162-A1 | Methods for lowering serum cholesterol | ELI LILLY AND COMPANY (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0651998-A1 | Methods for inhibiting bone loss | ELI LILLY AND COMPANY (US) | 1995-05-10 | — | — | EP | disclosed |
| EP-0650724-A1 | Methods for inhibiting uterine fibrosis | ELI LILLY AND COMPANY (US) | 1995-05-03 | — | — | EP | disclosed |
| US-5393763-A | Administering benzothiophenes such as raloxifene hydrochloride | ELI LILLY AND COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0635264-A2 | Antiestrogens as hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1995-01-25 | — | — | EP | disclosed |
| EP-0605193-A1 | Use of benzothiophenes for treatment of hypercholesterolaemia | ELI LILLY AND COMPANY (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0584952-A1 | Improvements in or relating to benzothiophenes | ELI LILLY AND COMPANY (US) | 1994-03-02 | — | — | EP | disclosed |