Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3038199 | 0.77 | TDP1 (0.41) | — | |
| SCHEMBL159889 | 0.75 | MAPT (0.43) | MAOAPTGS1LMNA | |
| SCHEMBL27946829 | 0.73 | DPP4 (0.32) | — | |
| SCHEMBL4714323 | 0.73 | — | — | |
| SCHEMBL27531239 | 0.73 | MAPT (0.39) | MAOAPTGS1LMNA | |
| SCHEMBL27982479 | 0.72 | PTGS1 (0.40) | MAOAPTGS1LMNA | |
| SCHEMBL11555241 | 0.72 | PTGS1 (0.40) | MAOAPTGS1LMNA | |
| SCHEMBL17133871 | 0.72 | PTGS1 (0.40) | MAOAPTGS1LMNA | |
| SCHEMBL27917023 | 0.72 | LMNA (0.64) | MAOAPTGS1LMNA | |
| SCHEMBL6622827 | 0.72 | LMNA (0.64) | MAOAPTGS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773797-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006014012-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-02-09 | — | — | WO | disclosed |