SCHEMBL5167640

SCHEMBL5167640

O=C1CCC(C(=O)c2ccccc2)=C1C(=O)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
LMNA P02545 4/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
XBP1 P17861 1/20 0.42
HKDC1 Q2TB90 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
SRD5A2 P31213 1/20 0.42
AKR1C3 P42330 1/20 0.39
TSHR P16473 2/20 0.38
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
CYP2C8 P10632 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8588451 0.74 SMN1; SMN2 (0.54) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL10192812 0.73 ALDH1A1 (0.43) ALDH1A1LMNAL3MBTL1MEN1KMT2A
SCHEMBL28178057 0.73 ALDH1A1 (0.59) ALDH1A1L3MBTL1ATMTDP1SRD5A2
SCHEMBL1628426 0.69 ALDH1A1 (0.59) ALDH1A1LMNAL3MBTL1MEN1KMT2A
Benzophenone SCHEMBL30536983 0.68 ALDH1A1 (1.00) ALDH1A1LMNAL3MBTL1MEN1KMT2A
Benzophenone SCHEMBL30537001 0.68 ALDH1A1 (1.00) ALDH1A1LMNAL3MBTL1MEN1KMT2A
Benzophenone SCHEMBL6061130 0.68 ALDH1A1 (1.00) ALDH1A1LMNAL3MBTL1MEN1KMT2A
Benzophenone SCHEMBL28491203 0.68 ALDH1A1 (1.00) ALDH1A1LMNAL3MBTL1MEN1KMT2A
Benzophenone SCHEMBL1074283 0.68 ALDH1A1 (1.00) ALDH1A1LMNAL3MBTL1MEN1KMT2A
Benzophenone SCHEMBL28180817 0.68 ALDH1A1 (1.00) ALDH1A1LMNAL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6548543-B1 Administering as antiinflammatory agents, fungicides, tumor necrosis factor inhibitors, immunomodulators, heat shock protein inductors, and cellular adhesion controllers TAKARA SHUZO CO., LTD. (JP) 2003-04-15 US claimed
CN-1323204-A Therapeutic or prophylactic agent comprising cyclopentenone compound as active ingredient TAKARA SHUZO CO (JP) 2001-11-21 CN claimed
EP-1112742-A1 REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT Takara Shuzo Co, Ltd. (JP) 2001-07-04 EP claimed
CN-112772553-B Method for cultivating cold-resistant rabbits 吉林康安兔业有限公司 2022-12-20 CN disclosed
CN-112772553-A Method for cultivating cold-resistant rabbits 吉林康安兔业有限公司 2021-05-11 CN disclosed
CN-100391446-C Feeding method and feed TAKARA SHUZO CO (JP) 2008-06-04 CN disclosed
CN-101161096-A Breeding method and feedingstuff TAKARA BIO INC (JP) 2008-04-16 CN disclosed
EP-1103255-B1 METHOD OF REARING AND FEEDS TAKARA BIO INC (JP) 2007-05-02 EP disclosed
CN-1250211-C Remediesor preventives containing cyclopentenone compounds as the active ingredient TAKARA SHUZO CO (JP) 2006-04-12 CN disclosed
CN-1225472-C 5-membered ring compounds TAKARA SHUZO CO (JP) 2005-11-02 CN disclosed
CN-1213744-C Remedies TAKARA SHUZO CO (JP) 2005-08-10 CN disclosed
CN-1323204-A Therapeutic or prophylactic agent comprising cyclopentenone compound as active ingredient TAKARA SHUZO CO (JP) 2001-11-21 CN disclosed
CN-1323315-A 5-membered ring compounds TAKARA SHUZO CO (JP) 2001-11-21 CN disclosed
CN-1315857-A Feeding method and feed TAKARA SHUZO CO (JP) 2001-10-03 CN disclosed
EP-1112742-A1 REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT Takara Shuzo Co, Ltd. (JP) 2001-07-04 EP disclosed
EP-1106624-A1 5-MEMBERED RING COMPOUNDS Takara Shuzo Co, Ltd. (JP) 2001-06-13 EP disclosed
EP-1103255-A1 METHOD OF REARING AND FEEDS Takara Shuzo Co, Ltd. (JP) 2001-05-30 EP disclosed
US-6136854-A ANTICANCER AGENTS; APOPTOSIS; BACTERICIDES TAKARA SHUZO CO. (JP) 2000-10-24 US disclosed
CN-1247528-A Cyclopentenone derivatives TAKARA SHUZO CO (JP) 2000-03-15 CN disclosed
EP-0976717-A1 CYCLOPENTENONE DERIVATIVES Takara Shuzo Co, Ltd. (JP) 2000-02-02 EP disclosed