Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10192812 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL3260879 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL4292937 | 0.79 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL12475080 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1L3MBTL1MAPTPOLB | |
| SCHEMBL5167640 | 0.74 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1L3MBTL1MAPTTDP1 | |
| SCHEMBL12052311 | 0.72 | CNR2 (0.51) | SMN1; SMN2ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL10526508 | 0.71 | MEN1 (0.43) | SMN1; SMN2ALDH1A1L3MBTL1MAPTTDP1 | |
| SCHEMBL17379395 | 0.70 | BUB1 (0.57) | SMN1; SMN2ALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL28178057 | 0.70 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1TDP1GAAATM | |
| Benzophenone SCHEMBL27766299 | 0.69 | ALDH1A1 (0.82) | SMN1; SMN2ALDH1A1L3MBTL1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244692-B2 | Substituted benzoylcyclohexane diones for use as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2007-07-17 | — | — | US | disclosed |
| WO-1998042648-A1 | 2-BENZOYLCYCLOHEXANE-1,3-DIONE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 1998-10-01 | — | — | WO | disclosed |