Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761657 | 0.90 | TDP1 (0.48) | TDP1ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL27937461 | 0.87 | ALDH1A1 (0.53) | TDP1ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL23451607 | 0.84 | ALDH1A1 (0.50) | TDP1ALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL11636699 | 0.82 | — | — | |
| SCHEMBL8474854 | 0.79 | ALDH1A1 (0.61) | TDP1ALDH1A1TSHRDNM1HSD17B10 | |
| SCHEMBL5948312 | 0.77 | DNM1 (0.48) | TDP1ALDH1A1TSHRDNM1CYP1A2 | |
| SCHEMBL5948612 | 0.77 | DNM1 (0.55) | TDP1ALDH1A1TSHRDNM1CYP1A2 | |
| SCHEMBL10735956 | 0.74 | ALDH1A1 (0.45) | TDP1ALDH1A1TSHRDNM1 | |
| SCHEMBL1417224 | 0.74 | ALDH1A1 (0.53) | TDP1ALDH1A1TSHRDNM1HSD17B10 | |
| SCHEMBL1613314 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773920-A1 | METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES | Wacker Chemie AG (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006015740-A1 | METHOD FOR THE PRODUCTION OF EMULSIONS OF HIGHLY-VISCOUS ORGANOPOLYSILOXANES | WACKER CHEMIE AG (DE) | 2006-02-16 | — | — | WO | disclosed |