SCHEMBL5167880

SCHEMBL5167880

CC1(C)CCCC(C)(C(N)N)C1.O=C(O)CCCCCCCCCCC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
TSHR P16473 5/20 0.38
LMNA P02545 4/20 0.38
NFKB1 P19838 1/20 0.38
PMP22 Q01453 1/20 0.38
GPR84 Q9NQS5 7/20 0.36
PPARG P37231 7/20 0.36
PPARD Q03181 7/20 0.36
PPARA Q07869 7/20 0.36
HDAC11 Q96DB2 5/20 0.36
PTPN1 P18031 3/20 0.36
TLR2 O60603 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 2/20 0.36
FABP4 P15090 2/20 0.36
ALOX15 P16050 2/20 0.36
KMT2A Q03164 2/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
SLC22A8 Q8TCC7 1/20 0.36
ESR1 P03372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL5171609 1.00 ALDH1A1 (0.39) ALDH1A1TSHRLMNANFKB1PMP22
Adipic Acid SCHEMBL9436956 0.72 LMNA (0.50) ALDH1A1TSHRLMNANFKB1PMP22
Sebacic Acid SCHEMBL5171614 0.71 TSHR (0.36) ALDH1A1TSHRLMNANFKB1PMP22
Sebacic Acid SCHEMBL2344968 0.67 TSHR (0.48) ALDH1A1TSHRLMNANFKB1PMP22
Sebacic Acid SCHEMBL8067661 0.67 TSHR (0.48) ALDH1A1TSHRLMNANFKB1PMP22
SCHEMBL585224 0.67 TSHR (0.36) TSHRNFKB1
Azelaic Acid SCHEMBL29465682 0.67 TSHR (0.67) ALDH1A1TSHRLMNANFKB1PMP22
Sebacic Acid SCHEMBL7179944 0.66 TSHR (0.46) ALDH1A1TSHRLMNANFKB1PMP22
Octanedioate SCHEMBL30741313 0.66 TSHR (0.46) ALDH1A1TSHRLMNANFKB1PMP22
Sebacic Acid SCHEMBL8958570 0.66 TSHR (0.56) ALDH1A1TSHRLMNANFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7267915-B2 Photoconductive element having an amorphous polymeric barrier layer EASTMAN KODAK COMPANY (US) 2007-09-11 US claimed
EP-1774408-A1 PHOTOCONDUCTIVE ELEMENT HAVING AMORPHOUS, POLYMERIC BARRIER LAYER EASTMAN KODAK COMPANY (US) 2007-04-18 EP claimed
WO-2006017012-A1 PHOTOCONDUCTIVE ELEMENT HAVING AMORPHOUS, POLYMERIC BARRIER LAYER EASTMAN KODAK COMPANY (US) 2006-02-16 WO claimed
US-20060008720-A1 Photoconductive element having an amorphous polymeric barrier layer EASTMAN KODAK COMPANY 2006-01-12 US claimed
US-7267915-B2 Photoconductive element having an amorphous polymeric barrier layer EASTMAN KODAK COMPANY (US) 2007-09-11 US disclosed
EP-1774408-A1 PHOTOCONDUCTIVE ELEMENT HAVING AMORPHOUS, POLYMERIC BARRIER LAYER EASTMAN KODAK COMPANY (US) 2007-04-18 EP disclosed
WO-2006017012-A1 PHOTOCONDUCTIVE ELEMENT HAVING AMORPHOUS, POLYMERIC BARRIER LAYER EASTMAN KODAK COMPANY (US) 2006-02-16 WO disclosed
US-20060008720-A1 Photoconductive element having an amorphous polymeric barrier layer EASTMAN KODAK COMPANY 2006-01-12 US disclosed