SCHEMBL5168002

SCHEMBL5168002

CCCCCCCCCCCCc1ccccc1OC(=O)Oc1ccccc1CCCCCCCCCCCC

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.71
THRB P10828 1/20 0.71
PPARA Q07869 3/20 0.57
PPARG P37231 2/20 0.57
LIPG Q9Y5X9 1/20 0.53
ALOX5 P09917 1/20 0.51
PTGS2 P35354 1/20 0.51
BID P55957 3/20 0.49
MCL1 Q07820 3/20 0.49
BCL2L1 Q07817 2/20 0.49
BAK1 Q16611 2/20 0.49
KAT8 Q9H7Z6 2/20 0.49
EP300 Q09472 1/20 0.49
KAT2A Q92830 1/20 0.49
KAT2B Q92831 1/20 0.49
KAT5 Q92993 1/20 0.49
SAE1 Q9UBE0 1/20 0.49
LTB4R Q15722 1/20 0.47
LTB4R2 Q9NPC1 1/20 0.47
CYSLTR2 Q9NS75 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL248237 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1837310 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL9007291 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1840469 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1836494 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1838091 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1838105 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1835981 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1842572 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL5165070 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1436343-B8 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GEN ELECTRIC (US) 2007-04-11 EP claimed
EP-1436343-B1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GEN ELECTRIC COMPANY A CORP OF (US) 2006-11-02 EP claimed
EP-1436343-A1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME General Electric Company A Corporation of the State of New York (US) 2004-07-14 EP claimed
WO-2003031497-A1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GENERAL ELECTRIC COMPANY (US) 2003-04-17 WO claimed
US-6500914-B1 MELT TRANSESTERIFICATION OF FREE HYDROXYL TERMINAL GROUPS WITH A DIARYL CARBONATE GENERAL ELECTRIC COMPANY 2002-12-31 US claimed
EP-1436343-B8 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GEN ELECTRIC (US) 2007-04-11 EP disclosed
EP-1436343-B1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GEN ELECTRIC COMPANY A CORP OF (US) 2006-11-02 EP disclosed
EP-1436343-A1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME General Electric Company A Corporation of the State of New York (US) 2004-07-14 EP disclosed
WO-2003031497-A1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GENERAL ELECTRIC COMPANY (US) 2003-04-17 WO disclosed
US-6500914-B1 MELT TRANSESTERIFICATION OF FREE HYDROXYL TERMINAL GROUPS WITH A DIARYL CARBONATE GENERAL ELECTRIC COMPANY 2002-12-31 US disclosed