SCHEMBL248237

SCHEMBL248237

CCCCCCCCCc1ccccc1OC(=O)Oc1ccccc1CCCCCCCCC

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 1/20 0.71
THRB P10828 1/20 0.71
PPARA Q07869 3/20 0.57
PPARG P37231 2/20 0.57
LIPG Q9Y5X9 1/20 0.53
ALOX5 P09917 1/20 0.51
PTGS2 P35354 1/20 0.51
BID P55957 3/20 0.49
MCL1 Q07820 3/20 0.49
BCL2L1 Q07817 2/20 0.49
BAK1 Q16611 2/20 0.49
KAT8 Q9H7Z6 2/20 0.49
EP300 Q09472 1/20 0.49
KAT2A Q92830 1/20 0.49
KAT2B Q92831 1/20 0.49
KAT5 Q92993 1/20 0.49
SAE1 Q9UBE0 1/20 0.49
LTB4R Q15722 1/20 0.47
LTB4R2 Q9NPC1 1/20 0.47
CYSLTR2 Q9NS75 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1837310 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL9007291 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1840469 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1836494 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1838091 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL5168002 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1838105 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1835981 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL1842572 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL5165070 1.00 THRA (0.71) THRATHRBPPARAPPARGLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1436343-B8 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GEN ELECTRIC (US) 2007-04-11 EP claimed
EP-1436343-B1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GEN ELECTRIC COMPANY A CORP OF (US) 2006-11-02 EP claimed
EP-1436343-A1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME General Electric Company A Corporation of the State of New York (US) 2004-07-14 EP claimed
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
WO-2003031497-A1 METHOD FOR END-CAPPING POLYCARBONATE RESINS AND COMPOSITION FOR USE IN SAME GENERAL ELECTRIC COMPANY (US) 2003-04-17 WO claimed
US-6500914-B1 MELT TRANSESTERIFICATION OF FREE HYDROXYL TERMINAL GROUPS WITH A DIARYL CARBONATE GENERAL ELECTRIC COMPANY 2002-12-31 US claimed
EP-0066546-B1 EPOXIDE RESIN COMPOSITIONS CONTAINING ESTERS AS A DILUTING AGENT AND HARDENING ACCELERATORS CIBA-GEIGY AG (CH) 1985-12-18 EP claimed
US-4414377-A Epoxide resin compositions containing esters as diluents and cure accelerators CIBA-GEIGY CORPORATION (US) 1983-11-08 US claimed
EP-0066546-A2 Epoxide resin compositions containing esters as a diluting agent and hardening accelerators CIBA-GEIGY AG (CH) 1982-12-08 EP claimed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
EP-3174935-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED OPTICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-21 EP disclosed
EP-3174934-B1 COPOLYCARBONATE COMPOUNDS WITH CYCLIC AND LINEAR OLIGOMERS AND IMPROVED RHEOLOGICAL PROPERTIES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-14 EP disclosed
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-04-13 US disclosed
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-10 US disclosed
EP-0273724-B1 ACID GAS SCRUBBING BY COMPOSITE SOLVENT-SWOLLEN MEMBRANES BEND RESEARCH, INC. (US) 1992-06-17 EP disclosed
EP-0336535-A1 Gas separation by composite solvent-swollen membranes BEND RESEARCH, INC. (US) 1989-10-11 EP disclosed
US-4824443-A HIGHLY POLAR SOLVENT BEND RESEARCH, INC. (US) 1989-04-25 US disclosed
EP-0273724-A2 Acid gas scrubbing by composite solvent-swollen membranes BEND RESEARCH, INC. (US) 1988-07-06 EP disclosed
US-4737166-A SEPARATION OF HYDROGEN SULFIDE AND CARBON DIOXIDE FROM HYDROGEN, CARBON MONOXIDE AND HYDROCARBON GASES; SUPPORTED POLYMER BEND RESEARCH, INC. (US) 1988-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer IDH3A, IDH2, IDH3B THRA 4860/4885THRB 4881/4885PPARA 3254/4885
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER IDH3A, IDH2, IDH3B THRA 4856/4885THRB 4879/4885PPARA 3187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.