SCHEMBL5168218

SCHEMBL5168218

O=C(O)C1CNCC(O)C1=O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IDUA P35475 1/20 0.32
MAN1B1 Q9UKM7 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2403645 0.86 TSHR (0.33) ALDH1A1
SCHEMBL23002195 0.77
Hydrochloric Acid SCHEMBL19138196 0.75
SCHEMBL4233982 0.68 ALDH1A1 (0.32) ALDH1A1
SCHEMBL3412783 0.68
SCHEMBL8630981 0.67 GRIA2 (0.34) ALDH1A1
SCHEMBL2572584 0.65 SLC6A1 (0.38) ALDH1A1
SCHEMBL9289233 0.64 TSHR (0.35) ALDH1A1
Hydrochloric Acid SCHEMBL8784902 0.64 SLC6A1 (0.36)
SCHEMBL4078884 0.63 ALDH1A1 (0.32) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773854-A2 AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF Sanofi-Aventis (FR) 2007-04-18 EP disclosed
WO-2006021653-A2 AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF SANOFI-AVENTIS (FR) 2006-03-02 WO disclosed