Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.45 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.45 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 2/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.45 |
| ▸ | MST1R | Q04912 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.45 |
| ▸ | PLK4 | O00444 | 1/20 | 0.45 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3011060 | 0.87 | GRK6 (0.44) | GRK6MAP4K4CLK4CSNK1G2MKNK2 | |
| SCHEMBL27676654 | 0.87 | ATM (0.41) | GRK6ALDH1A1 | |
| SCHEMBL939586 | 0.86 | CD74 (0.53) | ALDH1A1 | |
| SCHEMBL30425732 | 0.86 | CD74 (0.53) | ALDH1A1 | |
| SCHEMBL15094744 | 0.86 | KMT2A (0.49) | MAPTALDH1A1 | |
| SCHEMBL3065165 | 0.84 | PARP1 (0.46) | CLK4CSNK1G2KDRMAPK8CDK8 | |
| SCHEMBL13545042 | 0.84 | SMN1; SMN2 (0.41) | GRK6MAPK8CDK8MAPTALDH1A1 | |
| SCHEMBL1505455 | 0.84 | GABRG2 (0.50) | CDK8NPY5RMAPTALDH1A1 | |
| SCHEMBL13542931 | 0.84 | ACHE (0.38) | GRK6MAP4K4CLK4CSNK1G2MKNK2 | |
| Hydrochloric Acid SCHEMBL12469361 | 0.83 | MAP2K4 (0.45) | CLK4CSNK1G2KDRMAPK8CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773125-A1 | 5-IODOTETRAZOLES | Lanxess Deutschland GmbH (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006012996-A1 | 5-IODOTETRAZOLES | LANXESS DEUTSCHLAND GMBH (DE) | 2006-02-09 | — | — | WO | disclosed |