Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5169037 | 1.00 | HTR1A (0.91) | HTR1ADRD2 | |
| SCHEMBL5171063 | 1.00 | HTR1A (0.91) | HTR1ADRD2 | |
| SCHEMBL5169029 | 1.00 | HTR1A (0.91) | HTR1ADRD2 | |
| SCHEMBL8901025 | 0.81 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL8901033 | 0.81 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL8901881 | 0.81 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL8901029 | 0.81 | HTR1A (1.00) | HTR1ADRD2 | |
| SCHEMBL8170360 | 0.80 | HTR1A (0.65) | HTR1A | |
| SCHEMBL8170356 | 0.80 | HTR1A (0.65) | HTR1A | |
| Hydrochloric Acid SCHEMBL8900083 | 0.80 | HTR1A (1.00) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100780-B1 | 2,3,3a,4,9,9a-HEXAHYDRO-8-HYDROXY-1H-BENZ[F]INDOLES, A METHOD FOR THE PRODUCTION THEREOF, AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2007-04-25 | — | — | EP | disclosed |
| US-6051583-A | CARDIOVASCULAR DISORDERS; BRAIN DISORDERS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-04-18 | — | — | US | disclosed |