Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170360 | 1.00 | HTR1A (0.65) | HTR1ASIGMAR1TMEM97 | |
| SCHEMBL3176956 | 0.81 | HTR1A (0.51) | HTR1ASIGMAR1 | |
| SCHEMBL8301747 | 0.81 | HTR1A (0.51) | HTR1ASIGMAR1 | |
| SCHEMBL2885978 | 0.80 | SIGMAR1 (0.54) | HTR1ASIGMAR1 | |
| SCHEMBL5169033 | 0.80 | HTR1A (0.91) | HTR1A | |
| SCHEMBL5171063 | 0.80 | HTR1A (0.91) | HTR1A | |
| SCHEMBL5169037 | 0.80 | HTR1A (0.91) | HTR1A | |
| SCHEMBL5169029 | 0.80 | HTR1A (0.91) | HTR1A | |
| SCHEMBL2095757 | 0.75 | HTR1A (0.47) | HTR1ASIGMAR1 | |
| SCHEMBL22605206 | 0.75 | HTR1A (0.47) | HTR1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080752-A | FOR TREATING CONDITION WHICH REQUIRES ANTAGONISM OF A DOPAMINE RECEPTOR SUCH AS PSYCHTIC CONDITION | SMITHKLINE BEECHAM PLC (GB) | 2000-06-27 | — | — | US | disclosed |