SCHEMBL5169583

SCHEMBL5169583

C=C(CNC(C)C)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 8/20 0.62
MAOB P27338 8/20 0.62
ADRB2 P07550 2/20 0.42
ADRB1 P08588 2/20 0.42
ADRB3 P13945 2/20 0.42
MAPT P10636 3/20 0.41
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
XBP1 P17861 1/20 0.41
ATM Q13315 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP2D6 P10635 2/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9593617 0.86 MAOA (0.60) MAOAMAOBMAPTLMNASMN1; SMN2
SCHEMBL17329420 0.83 MAOA (0.56) MAOAMAOBMAPTLMNASMN1; SMN2
SCHEMBL2640025 0.81 MAOA (0.44) MAOAMAOBADRB2ADRB1ADRB3
Iodide SCHEMBL10767386 0.79 MAOA (0.56) MAOAMAOBLMNA
SCHEMBL16795730 0.79 MAOA (0.51) MAOAMAOBMAPTLMNASMN1; SMN2
SCHEMBL15922401 0.77 MAOA (0.59) MAOAMAOBMAPTLMNASMN1; SMN2
SCHEMBL1930695 0.77 MAOA (0.63) MAOAMAOBMAPTSMN1; SMN2MEN1
SCHEMBL1274666 0.77 MAOA (1.00) MAOAMAOBMAPTLMNASMN1; SMN2
SCHEMBL4102495 0.76 ALDH1A1 (0.57) ADRB2ADRB1ADRB3MAPTLMNA
Hydrochloric Acid SCHEMBL18953115 0.75 MAOA (1.00) MAOAMAOBMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9783671-B2 Cross-linked plastic material with an intrinsic antimicrobial effect based on unsaturated polyesters Fachhochschule Münster (DE) 2017-10-10 US claimed
EP-0052330-B1 NOVEL RESIN COMPOSITION, COATING MATERIAL COMPRISING SAID RESIN COMPOSITION AND METHOD FOR FORMING COATINGS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-09-05 EP claimed
US-4447580-A POLYMER CONSISTING OF UNSATD AROMATIC AMINE AND UNSATURATED COMPOUND WITH ELECTRON ATTRACTIVE GROUP ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-05-08 US claimed
EP-0052330-A1 Novel resin composition, coating material comprising said resin composition and method for forming coatings Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-05-26 EP claimed
US-10138307-B2 Antimicrobial polymer Fachhochschule Münster (DE) 2018-11-27 US disclosed
EP-2951216-B1 ANTI-MICROBIAL POLYMER FACHHOCHSCHULE MUENSTER (DE) 2018-07-18 EP disclosed
US-9803091-B2 Cross-linked plastic material with an intrinsic antimicrobial effect based on vinyl esters and vinyl ester urethanes Fachhochschule Münster (DE) 2017-10-31 US disclosed
US-9783671-B2 Cross-linked plastic material with an intrinsic antimicrobial effect based on unsaturated polyesters Fachhochschule Münster (DE) 2017-10-10 US disclosed
EP-2951245-B1 CROSSLINKED PLASTIC MATERIAL WITH INTRINSIC ANTIMICROBIAL EFFECT ON THE BASIS OF UNSATURATED POLYESTER Fachhochschule Münster (DE) 2017-08-02 EP disclosed
EP-2951243-B1 CROSSLINKED PLASTIC MATERIAL WITH INTRINSICALLY ANTIMICROBIAL EFFECT BASED ON VINYL ESTERS AND VINYL ESTERURETHANES Fachhochschule Münster (DE) 2017-03-08 EP disclosed
US-20150368380-A1 ANTIMICROBIAL POLYMER Fachhochschule Münster (DE) 2015-12-24 US disclosed
US-20150361277-A1 CROSS-LINKED PLASTIC MATERIAL WITH AN INTRINSIC ANTIMICROBIAL EFFECT BASED ON VINYL ESTERS AND VINYL ESTER URETHANES Fachhochschule Münster (DE) 2015-12-17 US disclosed
EP-1020426-B9 AMINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME POLA CHEM IND INC (JP) 2006-03-22 EP disclosed
EP-1561744-A2 AMINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS ANTIMYCOTIC AGENT POLA CHEMICAL INDUSTRIES INC. (JP) 2005-08-10 EP disclosed
EP-1020426-B1 AMINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME POLA CHEM IND INC (JP) 2005-07-13 EP disclosed
US-6329399-B1 Antifungal amine derivatives and processing for producing the same POLA CHEMICAL INDUSTRIES, INC. (JP) 2001-12-11 US disclosed
EP-1020426-A1 AMINE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME POLA CHEMICAL INDUSTRIES, INC. (JP) 2000-07-19 EP disclosed
EP-0052330-B1 NOVEL RESIN COMPOSITION, COATING MATERIAL COMPRISING SAID RESIN COMPOSITION AND METHOD FOR FORMING COATINGS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-09-05 EP disclosed
US-4447580-A POLYMER CONSISTING OF UNSATD AROMATIC AMINE AND UNSATURATED COMPOUND WITH ELECTRON ATTRACTIVE GROUP ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-05-08 US disclosed
EP-0052330-A1 Novel resin composition, coating material comprising said resin composition and method for forming coatings Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10138307-B2 Antimicrobial polymer PUF60, PARG, DPM1 MAOA 2890/4885MAOB 3333/4885ADRB2 4725/4885
US-20150368380-A1 ANTIMICROBIAL POLYMER PUF60, PARG, DPM1 MAOA 2890/4885MAOB 3333/4885ADRB2 4725/4885
US-20150361277-A1 CROSS-LINKED PLASTIC MATERIAL WITH AN INTRINSIC ANTIMICROBIAL EFFECT BASED ON VINYL ESTERS AND VINYL ESTER URETHANES PUF60, UROD, MYD88 MAOA 2718/4885MAOB 3564/4885ADRB2 4364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.