Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL377001 | 0.88 | MAPT (0.54) | ALDH1A1HTTMAPTLMNAGFER | |
| SCHEMBL27514040 | 0.87 | ALDH1A1 (0.52) | ALDH1A1HTTMAPTLMNAGFER | |
| SCHEMBL27527047 | 0.87 | MAPT (0.58) | ALDH1A1HTTMAPTLMNAGFER | |
| Hydrochloric Acid SCHEMBL27544061 | 0.85 | MAPT (0.56) | ALDH1A1HTTMAPTLMNAGFER | |
| SCHEMBL21694087 | 0.85 | MAPT (0.58) | ALDH1A1HTTMAPTLMNAGFER | |
| SCHEMBL13836776 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HTTMAPTLMNAGFER | |
| SCHEMBL28501630 | 0.82 | MAPT (0.51) | ALDH1A1HTTMAPTLMNAGFER | |
| SCHEMBL1039786 | 0.79 | HTT (0.56) | ALDH1A1HTTMAPTLMNAATM | |
| Benzophenone SCHEMBL7454682 | 0.78 | ALDH1A1 (0.88) | ALDH1A1MAPTLMNAATMTDP1 | |
| SCHEMBL3039645 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114479735-A | Cationic UV curing adhesive and preparation method and application thereof | 张河远 | 2022-05-13 | — | — | CN | claimed |
| EP-0209831-B1 | SUBSTITUTED BENZOPHENONES AND THEIR LIQUID MIXTURES SUITABLE FOR USE AS PHOTOPOLYMERISATION INITIATORS | FRATELLI LAMBERTI S.p.A. (IT) | 1990-05-16 | — | — | EP | claimed |
| US-4755541-A | Substituted benzophenones and their liquid mixtures suitable for use as photopolymerization initiators | FRATELLI LAMBERTI SPA (IT) | 1988-07-05 | — | — | US | claimed |
| EP-0209831-A2 | Substituted benzophenones and their liquid mixtures suitable for use as photopolymerisation initiators | FRATELLI LAMBERTI S.p.A. (IT) | 1987-01-28 | — | — | EP | claimed |
| CN-114479735-A | Cationic UV curing adhesive and preparation method and application thereof | 张河远 | 2022-05-13 | — | — | CN | disclosed |
| EP-1776100-B1 | TREATMENT OF CANCER USING BENZOIC ACID DERIVATIVES | UNIV NEW YORK (US) | 2016-08-31 | — | — | EP | disclosed |
| US-9018259-B2 | Treatment of cancer using benzoic acid derivatives | NEW YORK UNIVERSITY (US) | 2015-04-28 | — | — | US | disclosed |
| US-8512934-B2 | Sulphonium salt initiators | BASF SE (DE) | 2013-08-20 | — | — | US | disclosed |
| US-20120329861-A1 | TREATMENT OF CANCER USING BENZOIC ACID DERIVATIVES | NEW YORK UNIVERSITY (US) | 2012-12-27 | — | — | US | disclosed |
| US-8198328-B2 | Treatment of cancer using benzoic acid derivatives | NEW YORK UNIVERSITY (US) | 2012-06-12 | — | — | US | disclosed |
| US-8067643-B2 | Sulphonium salt initiators | BASF SE (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20100297542-A1 | SULPHONIUM SALT INITIATORS | BASF SE (DE) | 2010-11-25 | — | — | US | disclosed |
| EP-1776100-A2 | TREATMENT OF CANCER USING BENZOIC ACID DERIVATIVES | NEW YORK UNIVERSITY (US) | 2007-04-25 | — | — | EP | disclosed |
| US-20050209334-A1 | method of treating cancer using benzoic acid derivatives, alone or in combination with standard treatments such as chemotherapy and radiotherapy methods of screening for benzoic derivatives based on their ability to inhibit the enzyme tyrosinase or to bind to and activate PXR/SXR xenobiotic receptors. | NEW YORK UNIVERSITY (US) | 2005-09-22 | — | — | US | disclosed |
| WO-2005070024-A2 | TREATMENT OF CANCER USING BENZOIC ACID DERIVATIVES | NEW YORK UNIVERSITY (US) | 2005-08-04 | — | — | WO | disclosed |
| US-5354784-A | Photoinitiators for cationically polymerizable compounds | ARAKAWA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0209831-B1 | SUBSTITUTED BENZOPHENONES AND THEIR LIQUID MIXTURES SUITABLE FOR USE AS PHOTOPOLYMERISATION INITIATORS | FRATELLI LAMBERTI S.p.A. (IT) | 1990-05-16 | — | — | EP | disclosed |
| US-4755541-A | Substituted benzophenones and their liquid mixtures suitable for use as photopolymerization initiators | FRATELLI LAMBERTI SPA (IT) | 1988-07-05 | — | — | US | disclosed |
| EP-0209831-A2 | Substituted benzophenones and their liquid mixtures suitable for use as photopolymerisation initiators | FRATELLI LAMBERTI S.p.A. (IT) | 1987-01-28 | — | — | EP | disclosed |
| US-4071540-A | MALEIC OR PHTHALIC | CHEVRON RESEARCH COMPANY (US) | 1978-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297542-A1 | SULPHONIUM SALT INITIATORS | CBR1, CBR3, NCOR1 | ALDH1A1 2518/4885HTT 1409/4885MAPT 3855/4885 |
| US-20050209334-A1 | method of treating cancer using benzoic acid derivatives, alone or in combination with standard treatments such as chemotherapy and radiotherapy methods of screening for benzoic derivatives based on their ability to inhibit the enzyme tyrosinase or to bind to and activate PXR/SXR xenobiotic receptors. | AHR, TYR, CYP4X1 | ALDH1A1 598/4885HTT 3556/4885MAPT 3055/4885 |
| US-20120329861-A1 | TREATMENT OF CANCER USING BENZOIC ACID DERIVATIVES | AHR, TYR, CYP4X1 | ALDH1A1 453/4885HTT 3235/4885MAPT 2439/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.