SCHEMBL3039645

SCHEMBL3039645

Cc1cccc(C)c1C(=O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.59
ATM Q13315 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
SRD5A2 P31213 1/20 0.50
LMNA P02545 2/20 0.48
MAPT P10636 2/20 0.48
HPGD P15428 2/20 0.48
POLB P06746 1/20 0.48
HSD17B10 Q99714 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
PBRM1 Q86U86 1/20 0.47
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
AKR1C3 P42330 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
BCL2L1 Q07817 1/20 0.46
MYC P01106 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29215698 0.90 AKR1C3 (0.59) ALDH1A1ATMTDP1L3MBTL1MAPT
SCHEMBL31738885 0.87 MYC (0.57) ALDH1A1ATMTDP1L3MBTL1MAPT
SCHEMBL1667150 0.87 MYC (0.57) ALDH1A1ATMTDP1L3MBTL1MAPT
SCHEMBL14327926 0.87 MAPT (0.55) ALDH1A1ATML3MBTL1LMNAMAPT
SCHEMBL1913492 0.86 MAPT (0.55) ALDH1A1ATMTDP1L3MBTL1LMNA
SCHEMBL22182091 0.86 ALDH1A1 (0.48) ALDH1A1ATMTDP1L3MBTL1SRD5A2
SCHEMBL38662722 0.86 AKR1C3 (0.59) ALDH1A1ATMTDP1L3MBTL1SRD5A2
SCHEMBL51520 0.86 AKR1C3 (0.59) ALDH1A1ATMTDP1L3MBTL1SRD5A2
SCHEMBL28272899 0.86 CES2 (0.48) ALDH1A1ATMTDP1L3MBTL1SRD5A2
Benzophenone SCHEMBL2156249 0.85 ALDH1A1 (0.74) ALDH1A1ATMTDP1L3MBTL1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114479735-A Cationic UV curing adhesive and preparation method and application thereof 张河远 2022-05-13 CN claimed
CN-114479735-A Cationic UV curing adhesive and preparation method and application thereof 张河远 2022-05-13 CN disclosed
CN-111417901-A Resin composition for forming insulating film, method for producing resin composition for forming insulating film, dry film, printed wiring board, and method for producing printed wiring board 互应化学工业株式会社 2020-07-14 CN disclosed
US-20140154610-A1 AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND USES THEREOF JSR CORPORATION (JP) 2014-06-05 US disclosed
US-20140154610-A1 AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND USES THEREOF JSR CORPORATION (JP) 2014-06-05 US disclosed
EP-2738194-A1 AROMATIC COPOLYMER HAVING PROTON CONDUCTIVE GROUP AND APPLICATION THEREOF JSR Corporation (JP) 2014-06-04 EP disclosed
US-8263607-B2 1-substituted tetrahydroisoquinoline compound ASTELLAS PHARMA INC. (JP) 2012-09-11 US disclosed
EP-2096101-B1 Method for producing ketones from alpha-oxocarboxylates and aryl bromides SALTIGO GMBH (DE) 2012-04-18 EP disclosed
US-7781625-B2 Process catalysed by bis-trifilmide compounds THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2010-08-24 US disclosed
US-20100168154-A1 1-SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUND ASTELLAS PHARMA INC. (JP) 2010-07-01 US disclosed
US-6001883-A SUBSTITUTED BENZOPHENONES OF GIVEN FORMULA, SUCH AS 6,6'-DIMETHYL-2,2',3',4'-TETRAMETHOXY-5-TRIFLUOROMETHYL-BENZOPHENONE; HIGHLY SYSTEMIC FUNGICIDES; CONTROLLING FUNGAL DISEASE SUCH AS POWDERY MILDEW IN PLANTS AMERICAN CYANAMID COMPANY (US) 1999-12-14 US disclosed
US-5945567-A Fungicidal 2-methoxybenzophenones AMERICAN CYANAMID COMPANY (US) 1999-08-31 US disclosed
US-5922905-A INTERMEDIATES FOR FUNGICIDES AMERICAN CYANAMID COMPANY (US) 1999-07-13 US disclosed
EP-0897904-A1 Fungicidal 2-methoxybenzophenones American Cyanamid Company (US) 1999-02-24 EP disclosed
EP-0546133-B1 A METHOD FOR PREPARING ARYL KETONES VELSICOL CHEMICAL CORP (US) 1996-08-21 EP disclosed
US-5476970-A Reacting of an aromatic hydrocarbon and benzoyl peroxide VELSICOL CHEMICAL CORPORATION (US) 1995-12-19 US disclosed
US-5298664-A Benzophenone from benzene and benzoyl chloride, ferric chloride catalyst VELSICOL CHEMICAL CORPORATION (US) 1994-03-29 US disclosed
EP-0546133-A1 A METHOD FOR PREPARING ARYL KETONES. VELSICOL CHEMICAL CORP (US) 1993-06-16 EP disclosed
WO-1992021640-A1 A METHOD FOR PREPARING ARYL KETONES VELSICOL CHEMICAL CORPORATION (US) 1992-12-10 WO disclosed
US-3933917-A Production of dimethylbenzophenone BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100168154-A1 1-SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUND CACNA1S, CACNA1E, CACNA1B ALDH1A1 2410/4885ATM 4454/4885TDP1 3531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.