SCHEMBL5169870

SCHEMBL5169870

COC(=O)c1ccc(OC)c(C(=O)OC)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.64
KDM4E B2RXH2 6/20 0.58
ALDH1A1 P00352 5/20 0.58
HPGD P15428 3/20 0.58
HSD17B10 Q99714 3/20 0.58
ATM Q13315 2/20 0.58
GAA P10253 2/20 0.58
GLA P06280 1/20 0.58
CASP1 P29466 1/20 0.58
CASP7 P55210 1/20 0.58
KMT2A Q03164 5/20 0.57
MEN1 O00255 3/20 0.54
TDP1 Q9NUW8 1/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA12 O43570 1/20 0.53
CA7 P43166 1/20 0.53
XDH P47989 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29678875 1.00 MAPT (0.64) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL6931187 0.91 CYP1A2 (0.63) MAPTKDM4EALDH1A1HPGDATM
SCHEMBL129159 0.89 HDAC1 (0.57) MAPTKDM4EALDH1A1HPGDKMT2A
SCHEMBL5168276 0.89 CA12 (0.65) MAPTKDM4EALDH1A1HPGDGAA
SCHEMBL310059 0.89 MAPT (0.60) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL30456978 0.89 CA12 (0.65) MAPTKDM4EALDH1A1HPGDGAA
SCHEMBL1561739 0.89 MAPT (0.60) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL20944605 0.87 MAPK1 (0.55) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL8889303 0.87 MAPT (0.58) MAPTKDM4EALDH1A1HPGDHSD17B10
SCHEMBL25236981 0.87 MAPT (0.50) MAPTKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112159347-B Preparation method of picolitamide 常州工程职业技术学院 2022-06-07 CN claimed
CN-112159347-A Preparation method of picolitamide 常州工程职业技术学院 2021-01-01 CN claimed
CN-112159347-B Preparation method of picolitamide 常州工程职业技术学院 2022-06-07 CN disclosed
CN-112159347-B Preparation method of picolitamide 常州工程职业技术学院 2022-06-07 CN disclosed
CN-112159347-A Preparation method of picolitamide 常州工程职业技术学院 2021-01-01 CN disclosed
CN-112159347-A Preparation method of picolitamide 常州工程职业技术学院 2021-01-01 CN disclosed
EP-1065569-B1 Toner, two-component type developer, heat fixing method, image forming method and apparatus unit CANON KK (JP) 2007-05-02 EP disclosed
EP-1270558-B1 \"Compound for the treatment of atherosclerotic-thrombotic pathological conditions\ CASAGRANDE CESARE (IT) 2007-04-25 EP disclosed
US-6525078-B1 Compound for the treatment of atherosclerotic-thrombotic pathological conditions CASAGRANDE CESARE (IT) 2003-02-25 US disclosed
EP-1270558-A1 \"Compound for the treatment of atherosclerotic-thrombotic pathological conditions\ Casagrande, Cesare (IT) 2003-01-02 EP disclosed
US-5191121-A Sunscreen KAO CORPORATION (JP) 1993-03-02 US disclosed
US-5146002-A Sunscreen KAO CORPORATION (JP) 1992-09-08 US disclosed
EP-0416564-A2 Novel aroyl ketone derivative, UV ray absorber comprising the same, and cosmetic composition containing the same KAO CORPORATION (JP) 1991-03-13 EP disclosed