SCHEMBL129159

SCHEMBL129159

COC(=O)c1cc(C(C)=O)ccc1OC

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
AKR1C3 P42330 3/20 0.55
AKR1C2 P52895 3/20 0.55
MAPT P10636 3/20 0.51
KMT2A Q03164 5/20 0.51
ALDH1A1 P00352 4/20 0.51
MEN1 O00255 3/20 0.51
KDM4E B2RXH2 3/20 0.51
LMNA P02545 1/20 0.51
HDAC8 Q9BY41 2/20 0.50
HPGD P15428 1/20 0.50
CREBBP Q92793 1/20 0.49
HTT P42858 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29678875 0.89 MAPT (0.64) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL5169870 0.89 MAPT (0.64) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL6931187 0.87 CYP1A2 (0.63) MAPTKMT2AALDH1A1MEN1KDM4E
SCHEMBL12595464 0.87 HDAC1 (0.57) HDAC1HDAC6AKR1C3AKR1C2MAPT
SCHEMBL30462572 0.87 HDAC1 (0.57) HDAC1HDAC6AKR1C3AKR1C2MAPT
SCHEMBL13897134 0.86 RAB9A (0.49) HDAC1HDAC6AKR1C3AKR1C2MAPT
SCHEMBL1561739 0.86 MAPT (0.60) HDAC1HDAC6AKR1C3AKR1C2MAPT
SCHEMBL30456978 0.86 CA12 (0.65) AKR1C3AKR1C2MAPTKMT2AALDH1A1
SCHEMBL5168276 0.86 CA12 (0.65) AKR1C3AKR1C2MAPTKMT2AALDH1A1
SCHEMBL423047 0.86 KMT2A (0.60) HDAC1HDAC6AKR1C3AKR1C2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3881048-B1 DEVICE FOR REMOVING VOLATILE ORGANIC COMPOUNDS LETAT FRANCAIS REPRESENTE PAR LE MINI DE LINTERIEUR (FR) 2026-05-06 EP disclosed
US-20220170904-A1 SYSTEMS AND METHODS FOR MONITORING BIOLOGICAL TISSUE DEGRADATION ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2022-06-02 US disclosed
US-20210396629-A1 DEVICE FOR COLLECTING VOLATILE ORGANIC COMPOUNDS L'ETAT FRANÇAIS REPRÉSENTÉ PAR LE MINISTÈRE DE L'INTÉRIEUR (FR) 2021-12-23 US disclosed
EP-3881048-A1 DEVICE FOR REMOVING VOLATILE ORGANIC COMPOUNDS L'etat Français Représenté Par Le Ministère De L'intérieur (FR) 2021-09-22 EP disclosed
CN-113167695-A Device for collecting volatile organic compounds 法国由内政部代表 2021-07-23 CN disclosed
WO-2020099735-A1 DEVICE FOR REMOVING VOLATILE ORGANIC COMPOUNDS L'ETAT FRANÇAIS REPRÉSENTÉ PAR LE MINISTÈRE DE L'INTÉRIEUR (FR) 2020-05-22 WO disclosed
US-9133073-B2 Compounds for the treatment of metabolic disorders WELLSTAT THERAPEUTICS CORPORATION (US) 2015-09-15 US disclosed
US-8604083-B2 Method for the treatment of metabolic disorders WELLSTAT THERAPEUTICS CORPORATION (US) 2013-12-10 US disclosed
US-20130281705-A1 COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS WELLSTAT THERAPEUTICS CORP (US) 2013-10-24 US disclosed
US-8552062-B2 Methods for the treatment of metabolic disorders such as diabetes WELLSTAT THERAPEUTICS CORPORATION (US) 2013-10-08 US disclosed
US-20030149107-A1 Compounds for the treatment of metabolic disorders PHARMA CINQ, LLC 2003-08-07 US disclosed
EP-1289980-A1 BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES SMITHKLINE BEECHAM PLC (GB) 2003-03-12 EP disclosed
WO-2002100341-A2 COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS WELLSTAT THERAPEUTICS CORPORATION (US) 2002-12-19 WO disclosed
WO-2001090100-A1 BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES SMITHKLINE BEECHAM P.L.C. (GB) 2001-11-29 WO disclosed
EP-0733037-A1 ARYL SUBSTITUTED AMINO ACIDS, CNS INFLUENCING AGENTS UNIVERSITY OF BRISTOL (GB) 1996-09-25 EP disclosed
US-5502187-A Pharmaceutically active bicyclic-heterocyclic amines THE UPJOHN COMPANY (US) 1996-03-26 US disclosed
WO-1995015941-A1 ARYL SUBSTITUTED AMINO ACIDS, CNS INFLUENCING AGENTS UNIVERSITY OF BRISTOL (GB) 1995-06-15 WO disclosed
EP-0633886-A1 PHARMACEUTICALLY ACTIVE BICYCLIC-HETEROCYCLIC AMINES PHARMACIA & UPJOHN COMPANY (US) 1995-01-18 EP disclosed
WO-1993020078-A1 PHARMACEUTICALLY ACTIVE BICYCLIC-HETEROCYCLIC AMINES THE UPJOHN COMPANY (US) 1993-10-14 WO disclosed
US-4221808-A Novel antihypertensive agent RICHARDSON-MERRELL INC. (US) 1980-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281705-A1 COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS GOT2, OAT, CPT1B HDAC1 1030/4885HDAC6 1460/4885AKR1C3 349/4885
US-20030149107-A1 Compounds for the treatment of metabolic disorders GOT2, OAT, CPT1B HDAC1 1030/4885HDAC6 1460/4885AKR1C3 349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.